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Merck

1003009

USP

Acetaminophen

United States Pharmacopeia (USP) Reference Standard

동의어(들):

Acetaminophen, 4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
CH3CONHC6H4OH
CAS 번호:
103-90-2
Molecular Weight:
151.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329748124
MDL number:
MFCD00002328
Beilstein/REAXYS Number:
2208089

주요 문서

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InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

SMILES string

CC(=O)Nc1ccc(O)cc1

grade

pharmaceutical primary standard

API family

acetaminophen, paracetamol

manufacturer/tradename

USP

Gene Information

human ... FAAH(2166), PTGS1(5742), PTGS2(5743), TRPV1(7442)

application(s)

pharmaceutical (small molecule)

format

neat

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Acetaminophen USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Acetaminophen Tablets
  • Acetaminophen Capsules
  • Acetaminophen Suppositories
  • Acetaminophen Oral Suspension
  • Acetaminophen Oral Solution
  • Acetaminophen and Caffeine Tablets
  • Acetaminophen Extended-Release Tablets

Analgesic.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

저장 등급

11 - Combustible Solids

flash_point_f

364.3 °F - Pensky-Martens closed cup

flash_point_c

184.6 °C - Pensky-Martens closed cup

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Acetaminophen
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(6), 38-38 (2020)
Acetaminophen capsules
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 45(3), 40-40 (2014)
Acetaminophen tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(3), 45-45 (2021)
Acetaminophen Suppositories
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(5), 44-44 (2016)
Mitchell R McGill et al.
Pharmaceutical research, 30(9), 2174-2187 (2013-03-07)
Acetaminophen (APAP) is one of the most widely used drugs. Though safe at therapeutic doses, overdose causes mitochondrial dysfunction and centrilobular necrosis in the liver. The first studies of APAP metabolism and activation were published more than 40 years ago.
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