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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C17H27NO2 · HCl
CAS 번호:
Molecular Weight:
313.86
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
pharmaceutical primary standard
API family
venlafaxine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
Cl[H].COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2
InChI
1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
InChI key
QYRYFNHXARDNFZ-UHFFFAOYSA-N
Gene Information
human ... SLC6A2(6530), SLC6A4(6532)
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Venlafaxine hydrochloride USP reference standard intended for use in specified quality tests and assays.
Also used to prepare standard, system suitability, and standard stock solution for assay, impurity analysis, and performance test according to the given below monographs of United States Pharmacopeia (USP):
Also used to prepare standard, system suitability, and standard stock solution for assay, impurity analysis, and performance test according to the given below monographs of United States Pharmacopeia (USP):
- Venlafaxine Hydrochloride
- Venlafaxine Tablets
- Venlafaxine Hydrochloride Extended-Release Capsules
- Desvenlafaxine
Biochem/physiol Actions
Venlafaxine is a dual serotonin-noradrenaline reuptake inhibitor that displays Ki values of 82 and 2480 nM respectively. It is a general class antidepressant.
Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 2
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Desvenlafaxine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(5), 1280-1280 (2020)
Venlafaxine Hydrochloride Extended-Release Capsules
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4598-4598 (2022)
Venlafaxine Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(3), 4595-4595 (2017)
Venlafaxine Hydrochloride
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(1), 4597-4597 (2020)
Denise G Tate et al.
Archives of physical medicine and rehabilitation, 96(2), 340-348 (2014-12-03)
To assess the role that treatment response plays in a randomized controlled trial of an antidepressant among people with spinal cord injury (SCI) diagnosed with major depressive disorder (MDD) in explaining quality of life (QOL), assessed both globally as life
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