Iniciar sesión para ver los precios por organización y contrato.
Seleccione un Tamaño
Acerca de este artículo
Fórmula lineal:
FC6H4C≡CH
Número CAS:
Peso molecular:
120.12
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1099285
Assay:
99%
Form:
solid
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarleServicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarleassay
99%
form
solid
refractive index
n20/D 1.516 (lit.)
bp
55-56 °C/40 mmHg (lit.)
mp
26-27 °C (lit.)
density
1.048 g/mL at 25 °C (lit.)
functional group
fluoro
storage temp.
2-8°C
SMILES string
Fc1ccc(cc1)C#C
InChI
1S/C8H5F/c1-2-7-3-5-8(9)6-4-7/h1,3-6H
InChI key
QXSWHQGIEKUBAS-UHFFFAOYSA-N
Categorías relacionadas
General description
1-Ethynyl-4-fluorobenzene (pFAB) is a fluorobenzene derivative. Trianionic pincer alkylidyne complex catalyzed polymerization of 1-ethynyl-4-fluorobenzene has been reported. The surface of the iodophenyl-terminated organic monolayers has been modified by Sonogashira coupling of the iodophenyl groups found on the surface with pFAB. Dimerization catalyzed by Y[N(TMS)2]3 and 4-chloroaniline gave exclusive formation of one of three possible enediynes in excellent yield.
Application
1-Ethynyl-4-fluorobenzene, a substituted phenylacetylene, may be used in the synthesis of aryl acetylenes, via Sonogashira type cross coupling reaction with various haloarenes in the presence of bis(μ-iodo)bis((-)-sparteine)dicopper(I) catalyst.
1-Ethynyl-4-fluorobenzene may be used in the synthesis of the following:
- 3-(4-Fluorophenyl)-1H-isochromen-1-one by reacting with 2-iodobenzoic acid in the presence of copper catalyst.
- 4-Bromo-3,5-difluoro-2,6-bis-(4-fluoro-phenylethynyl)-pyridine by reacting with 2,4,6-tribromo-3,5-difluoropyridine by palladium catalyzed Sonogashira reaction.
- 1-(4-Fluorophenyl)-3-methoxy-3-(4-methoxyphenyl)propan-1-one by reacting with p-anisaldehyde.
- 5-(4-Fluorophenyl)-1-(2-nitrobenzyl)-1H-1,2,3-triazole by reacting with 1-(bromomethyl)-2-nitrobenzene in the presence of sodium azide.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Sol. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Clase de almacenamiento
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
84.2 °F - closed cup
flash_point_c
29 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Soumya Sarkar et al.
Journal of the American Chemical Society, 134(10), 4509-4512 (2012-02-23)
Synthesis, characterization, and catalytic alkyne polymerization results for the first trianionic pincer alkylidyne complex, [(t)BuOCO]W≡CC(CH(3))(3)(THF)(2) (6), are described. Complex 6 is a highly active catalyst for the polymerization of acetylenes and exhibits a high turnover number (4371), activity (1.05 ×
Novel regio-and stereoselective dimerization of terminal alkynes catalyzed by rare-earth silylamide.
Komeyama K, et al.
Synthesis, 7, 1062-1066 (2004)
Bis (μ-iodo) bis ((-)-sparteine) dicopper (I) catalyzed Sonogashira-type reaction under palladium and phosphine-free conditions.
Priyadarshini S, et al.
Tetrahedron Letters, 52(14), 1615-1618 (2011)
Intermolecular Gold (I)-Catalyzed Alkyne Carboalkoxylation Reactions for the Multicomponent Assembly of β-Alkoxy Ketones.
Schultz DM, et al.
Advanced Synthesis & Catalysis, 354(18), 3451-3455 (2012)
Polyhalogenoheterocyclic compounds. Part 53. Sonogashira reactions of 2, 4, 6-tribromo-3, 5-difluoropyridine.
Howardb JAK.
ARKIVOC (Gainesville, FL, United States), 11, 46-55 (2007)
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico