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Merck

PHR1090

Dopamina hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

2-(3,4-Dihidroxifenil)etilamina hydrochloride, 3,4-Dihidroxifenetilamina hydrochloride, 3-Hidroxitiramina hydrochloride, 4-(2-Aminoetil)-1,2-bencenodiol hydrochloride

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Fórmula lineal:
(HO)2C6H3CH2CH2NH2·HCl
Número CAS:
62-31-7
Peso molecular:
189.64
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823112
EC Number:
200-527-8
Beilstein/REAXYS Number:
3656720
MDL number:
MFCD00012898

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InChI

1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H

InChI key

CTENFNNZBMHDDG-UHFFFAOYSA-N

SMILES string

Cl[H].NCCc1ccc(O)c(O)c1

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. D2690000, traceable to USP 1225204

API family

dopamine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

248-250 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

Gene Information

human ... ADRB1(153)

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Dopamine is a neurotransmitter which is a naturally occurring catecholamine. Dopamine hydrochloride salt is indicated as a medicine for the treatment of acute congestive and renal failures.

Application

Dopamine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry, colorimetry and chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7131 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Intropin (dopamine hydrochloride) intravenous admixture compatibility
Gardella LA, et al.
American Journal of Hospital Pharmacy, 32(6), 575-578 (1975)
Rapid Spectrophotometric Determination Of Dopamine Hydrochloride With Chloramine - T
Nagaraja P, et al.
Indian Journal of Pharmaceutical Sciences, 60(2), 99-99 (2016)
Spectrophotometric methods for the determination of certain catecholamine derivatives in pharmaceutical preparations
Nagaraja P, et al.
Talanta, 46(1), 39-44 (1998)
Darae Kang et al.
Poultry science, 100(3), 100964-100964 (2021-03-04)
The effects of early heat conditioning on the acute heat stress response in broilers were investigated via the growth performance, dopamine, serotonin, and corticosterone and the expression of heat shock proteins (HSP) and heat shock factors. One-day-old chicks (n =
A Jon Stoessl et al.
Lancet (London, England), 384(9942), 532-544 (2014-06-24)
Recent advances in structural and functional imaging have greatly improved our ability to assess normal functions of the basal ganglia, diagnose parkinsonian syndromes, understand the pathophysiology of parkinsonism and other movement disorders, and detect and monitor disease progression. Radionuclide imaging
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