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Merck

PHR1150

4-Nitrophenol

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

p-Nitrophenol

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Fórmula lineal:
O2NC6H4OH
Número CAS:
100-02-7
Peso molecular:
139.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823168
EC Number:
202-811-7
Beilstein/REAXYS Number:
1281877
MDL number:
MFCD00007331

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Nombre del producto

4-Nitrophenol, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

BTJIUGUIPKRLHP-UHFFFAOYSA-N

InChI

1S/C6H5NO3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H

SMILES string

O=N(C1=CC=C(O)C=C1)=O

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1003064

vapor pressure

0.6 mmHg ( 120 °C)

API family

acetaminophen, paracetamol

CofA

current certificate can be downloaded

autoignition temp.

541 °F

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

279 °C (lit.)

mp

110-115 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA8987 in the slot below. This is an example certificate only and may not be the lot that you receive.
Values of analytes vary lot to lot.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 2 - STOT RE 2 Oral

target_organs

Kidney,Liver

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

336.2 °F

flash_point_c

169 °C

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Alex V Birk et al.
The Journal of laboratory and clinical medicine, 140(3), 166-175 (2002-09-25)
Extracellular adenosine triphosphate (ATP) regulates platelet reactivity by way of direct action on platelet purinergic receptors or by hydrolysis to adenosine diphosphate (ADP). Subsequent metabolism of ATP and ADP to adenosine monophosphate (AMP) and adenosine inhibits platelet aggregation. Endothelial cell
Ali Mehdinia et al.
Journal of chromatography. A, 1283, 82-88 (2013-03-08)
In this study, an analytical procedure for the selective extraction and detection of 4-nitrophenol (4-NP) was investigated by using of molecularly imprinted polymer on the surface of magnetic nanoparticles (MNPs). The magnetic nanoparticles were modified by tetraethyl orthosilicate (TEOS) and
Ipsita K Sen et al.
Carbohydrate polymers, 91(2), 518-528 (2012-11-06)
Gold nanoparticles were synthesized by reducing chloroauric acid with a glucan, isolated from an edible mushroom Pleurotus florida, cultivar Assam Florida. Here, glucan acts as reducing as well as stabilizing agent. The synthesized gold nanoparticles were characterized by UV-visible spectroscopy
Simon De Corte et al.
Colloids and surfaces. B, Biointerfaces, 102, 898-904 (2012-10-31)
An increasing demand for catalytic Pd nanoparticles has motivated the search for sustainable production methods. An innovative approach uses bacterial cells as support material for synthesizing Pd nanoparticles by reduction of Pd(II) with e.g. hydrogen or formate. Nevertheless, drawbacks of
Siew Hong Lam et al.
Biochimica et biophysica acta, 1830(10), 4778-4789 (2013-06-25)
4-Nitrophenol (4-NP) is a prioritized environmental pollutant and its toxicity has been investigated using zebrafish, advocated as an alternative toxicological model. However, molecular information of 4-NP induced hepatotoxicity is still limited. This study aimed to obtain molecular insights into 4-NP-induced
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