B8279

Ro-20-1724

Name: Ro-20-1724
Brand: SIGMA

≥98% (HPLC), solid, cAMP phosphodiesterase inhibitor

Sinónimos:

Ro 20-1724

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About This Item

Fórmula empírica (notación de Hill):

C₁₅H₂₂N₂O₃

Número CAS:

29925-17-5

Peso molecular:

278.35

UNSPSC Code:

41106305

PubChem Substance ID:

24278195

NACRES:

NA.77

MDL number:

MFCD00077397

Nombre del producto

4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one, solid

SMILES string

CCCCOc1cc(CC2CNC(=O)N2)ccc1OC

InChI

1S/C15H22N2O3/c1-3-4-7-20-14-9-11(5-6-13(14)19-2)8-12-10-16-15(18)17-12/h5-6,9,12H,3-4,7-8,10H2,1-2H3,(H2,16,17,18)

InChI key

PDMUULPVBYQBBK-UHFFFAOYSA-N

biological source

synthetic (organic)

assay

≥98% (HPLC)

form

solid

solubility

ethanol: 7 mg/mL
H₂O: insoluble

storage temp.

room temp

Application

4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one has been used:

as a cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitor to treat cells for the determination of intracellular cAMP levels
as a component of serum-free medium
as phosphodiesterase inhibitor in order to study the effects of protease-activated receptor-1 (PAR-1) activation on cAMP levels

Biochem/physiol Actions

Inhibitor of cAMP phosphodiesterase. IC₅₀ 33 μM in vascular smooth muscle of the aorta.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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