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Merck

L3262

Anti-Lactoferrin antibody produced in rabbit

fractionated antiserum, lyophilized powder

Sinónimos:

Anti-Draculin, Anti-Draculin-1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:

Nombre del producto

Anti-Lactoferrin antibody produced in rabbit, fractionated antiserum, lyophilized powder

biological source

rabbit

conjugate

unconjugated

antibody form

fractionated antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

packaging

vial of 2 mL lyophilized antiserum

technique(s)

direct ELISA: 1:10,000 using using human lactoferrin

UniProt accession no.

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... LTF(4057)

Preparation Note

Reconstitute with 2 ml deionized water.

Application

Anti-Lactoferrin antibody produced in rabbit has been used in:
  • western blotting
  • indirect immunofluorescence
  • flow cytometry
  • enzyme-linked immunosorbent assay (ELISA)

Biochem/physiol Actions

A primary function of lactoferrin is to bind and transport iron ions. However, lactoferrin is also an effective antibacterial, antiviral, antiparasitic, catalytic (RNA degrading), anti-cancer molecule. It elicits anti-inflammatory effects in asthma. It has immunomodulatory and anti-inflammatory functionality and is a potential protein nutraceutical.
Rabbit polyclonal anti-lactoferrin antibody reacts with purified lactoferrin and human milk, but does not react with human serum proteins.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Lactoferrin, globular glycoprotein belongs to transferrin protein family. It is mapped to human chromosome 3p21.31. Lactoferrin comprises 692 amino acids with two globular lobes linked by α-helix and belongs to transferrin family. It exists in three isoforms namely lactoferrin-α, lactoferrin-γ, and lactoferrin-β. Lactoferrin corresponds to a molecular weight of 80 kDa.

Physical form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Genetic and epigenetic inactivation of LTF gene at 3p21. 3 in lung cancers
Iijima H, et al.
International Journal of Cancer. Journal International Du Cancer, 118(4), 797-801 (2006)
Neutrophil extracellular traps contain selected antigens of anti-neutrophil cytoplasmic antibodies
Panda R, et al.
Frontiers in Immunology, 8(2), 439-439 (2017)
Allergens induce the release of lactoferrin by neutrophils from asthmatic patients
Fernandez-Delgado L, et al.
Testing, 10(10), e0141278-e0141278 (2015)
Studying lactoferrin N-glycosylation
Karav S, et al.
International Journal of Molecular Sciences, 18(4), 870-870 (2017)
Expression, purification, and breast cancer cell inhibiting effect of recombinant human lactoferrin C-lobe
Hu L, et al.
Bioscience, Biotechnology, and Biochemistry, 80(2), 257-263 (2016)

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