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Merck

P9625

Phenazine methosulfate

powder, electron acceptor

Sinónimos:

5-Methylphenazinium methyl sulfate, N-Methylphenazonium methyl sulfate, PMS

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About This Item

Fórmula lineal:
C13H11N2 · CH3SO4
Número CAS:
Peso molecular:
306.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
206-072-1
MDL number:
Beilstein/REAXYS Number:
3898869

Nombre del producto

Phenazine methosulfate,

InChI key

RXGJTUSBYWCRBK-UHFFFAOYSA-M

InChI

1S/C13H11N2.CH4O4S/c1-15-12-8-4-2-6-10(12)14-11-7-3-5-9-13(11)15;1-5-6(2,3)4/h2-9H,1H3;1H3,(H,2,3,4)/q+1;/p-1

SMILES string

COS([O-])(=O)=O.C[n+]1c2ccccc2nc3ccccc13

form

powder

λ

0.01 g/L in H2O, 1 cm path

UV absorption

λ: 387.5 nm Amax

antibiotic activity spectrum

fungi

mode of action

DNA synthesis | interferes
cell membrane | interferes

storage temp.

−20°C

Quality Level

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Application

Phenazine methosulfate is used with ascorbic acid to determine nitric oxide reductase activity.
Phenazine methosulfate has been used:
  • as a component of succinate dehydrogenase enzyme substrate solution
  • to induce superoxide radical generation in red blood cell suspensions and to study its influence on RBC deformability
  • as a component of complex II histochemistry media

Biochem/physiol Actions

Phenazine m ethosulfate (PMS) acts as a good electron acceptor. PMS is reduced non-enzymatically by (nicotinamide adenine dinucleotide) NADH and (nicotinamide adenine dinucleotide phosphate) NADPH.

General description

Phenazines are heterocyclic compounds produced as secondary metabolites by bacteria.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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