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NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
mouse ... Il10(16153)
Input:
sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type serum
sample type plasma
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
Servicio técnico
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Permítanos ayudarleServicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarlespecies reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/mL
standard curve range: 78.13-5000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Il10(16153)
Categorías relacionadas
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
IL-10 (interleukin 10) is an anti-inflammatory cytokine. In mouse, IL-10 produced by the CD4+ Th2 (T helper cell 2) subset, inhibits the expression of cytokines specifically IFN-3 (interferon), by Thl (T helper cell 1) clones. mIL-10 has pleiotropic property and it interacts with various cell types such as thymocytes, cytotoxic T cells, mast cells, B cells, and macrophages. Polymorphisms in the IL-10 gene are associated with higher risk of preeclampsia, ankylosing spondylitis, nasopharyngeal carcinoma and basal cell carcinoma. B- cell specific IL-10 might have a suppressive role in systemic lupus erythematosus (SLE).
General description
The Mouse IL-10 (Interleukin-10) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of IL-10 in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Mouse IL-10
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Los componentes del kit también están disponibles por separado
Referencia del producto
Descripción
SDS
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Clase de almacenamiento
8A - Combustible corrosive hazardous materials
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Clinical significance of IL-2 and IL-10 gene polymorphisms and serum levels in patients with basal-cell carcinoma.
Sobjanek M
Biomarkers in Medicine, 10(2), 185-195 (2016)
Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.
de Waal Malefyt R
The Journal of Experimental Medicine, 174(5), 1209-1220 (1991)
IL-10 Production Is Critical for Sustaining the Expansion of CD5+ B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice.
Baglaenko Y
PLoS ONE, 11(3), e0150515-e0150515 (2016)
Investigations into the association between polymorphisms in the interleukin-10 gene and risk of early-onset preeclampsia.
Liu QY
Genetics and molecular research : GMR, 14(4), 19323-19328 (2015)
Interleukin-10 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis.
Yu YF
Genetics and molecular research : GMR, 14(4), 18945-18957 (2015)
Contenido relacionado
Instructions
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico