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Merck

S9692

SU 6656

≥98% (HPLC)

Sinónimos:

2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide

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Fórmula empírica (notación de Hill):
C19H21N3O3S
Número CAS:
330161-87-0
Peso molecular:
371.45
NACRES:
NA.77
PubChem Substance ID:
24278818
UNSPSC Code:
12352200
MDL number:
MFCD10565928
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
Storage condition:
protect from light, under inert gas

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InChI

1S/C19H21N3O3S/c1-22(2)26(24,25)14-7-8-18-15(11-14)16(19(23)21-18)10-13-9-12-5-3-4-6-17(12)20-13/h7-11,20H,3-6H2,1-2H3,(H,21,23)/b16-10-

SMILES string

CN(C)S(=O)(=O)c1ccc2NC(=O)C(=C/c3cc4CCCCc4[nH]3)\c2c1

InChI key

LOGJQOUIVKBFGH-YBEGLDIGSA-N

assay

≥98% (HPLC)

form

powder

storage condition

protect from light, under inert gas

color

orange-brown

solubility

DMSO: 12 mg/mL (orange solution)

storage temp.

−20°C

Quality Level

100

Gene Information

human ... SRC(6714)

Categorías relacionadas

Biochem/physiol Actions

SU 6656 is a selective Src family kinase inhibitor.
SU 6656 is a selective Src family kinase inhibitor. SU 6656 inhibits Src kinase in CD34 positively-selected umbilical cord blood cells.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000285359
0000236874
0000223825
0000223825
0000236874

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Evan L Nichols et al.
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Regeneration following spinal root avulsion is broadly unsuccessful despite the regenerative capacity of other PNS-located nerves. By combining focal laser lesioning to model root avulsion in zebrafish, time-lapse imaging, and transgenesis, we identify that regenerating DRG neurons fail to recapitulate
Shutang Zhou et al.
American journal of physiology. Cell physiology, 290(2), C463-C471 (2005-09-16)
Cortactin, a predominant substrate of Src family kinases, plays an important role in Arp2/3-dependent actin polymerization in lamellipodia and membrane ruffles and was recently shown to be enriched in podosomes induced by either c-Src or phorbol ester. However, the mechanisms
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