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Merck

1677002

USP

Triamcinolone acetonide

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

9α-Fluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide, 9α-Fluoro-16α-hydroxyprednisolone 16α,17α-acetonide

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Fórmula empírica (notación de Hill):
C24H31FO6
Número CAS:
76-25-5
Peso molecular:
434.50
NACRES:
NA.24
PubChem Substance ID:
329751377
UNSPSC Code:
41116107
MDL number:
MFCD00056834

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InChI

1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO

InChI key

YNDXUCZADRHECN-JNQJZLCISA-N

grade

pharmaceutical primary standard

API family

triamcinolone

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... NR3C1(2908)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Triamcinolone acetonide USP reference standard intended for use in specified quality tests and assays.

Also used to prepare system suitability, standard, and standard stock solution for assay, impurity analysis, and performance tests according to the given below monographs of United States Pharmacopeia (USP):
  • Triamcinolone Hexacetonide
  • Triamcinolone Acetonide Injectable Suspension
  • Triamcinolone Acetonide Nasal Spray

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

hcodes

H302,H360

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Triamcinolone Acetonide Nasal Spray
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(5) (2021)
Triamcinolone Acetonide Injectable Suspension
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(3), 4490-4490 (2020)
Triamcinolone Hexacetonide
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 36(5), 4492-4492 (2020)
Mazen Abu-Mugheisib et al.
Current pharmaceutical design, 18(29), 4564-4569 (2012-05-23)
Multiple sclerosis (MS) as a chronic disease presents a vast variability of neurological symptoms. Spasticity is one of the most common symptoms. The principle indication to treat spasticity is disability or handicap of capabilities. All pharmacological methods are attributed to
E M Becerra et al.
Current drug targets, 12(2), 149-172 (2010-10-05)
Triamcinolone acetonide (TA) is one of the first pharmacologic compounds evaluated for the treatment of choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). The most important effects of TA consist in the stabilisation of the blood-retinal barrier and the
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