Cobalt in waste water from coating resins and coating materials
- Document Type:
- Application
- Product Catalog Number:
- Multiple
- Product Catalog Name:
- Multiple
4452-06-6
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Cobalt in waste water from printing plates, print materials, and graphic products
- Document Type:
- Application
- Product Catalog Number:
- Multiple
- Product Catalog Name:
- Multiple
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Cobalt in waste water from metal processing and metal-working processes
- Document Type:
- Application
- Product Catalog Number:
- Multiple
- Product Catalog Name:
- Multiple
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Cobalt in waste water from the production of ceramics
- Document Type:
- Application
- Product Catalog Number:
- Multiple
- Product Catalog Name:
- Multiple
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Cobalt in waste water from the production of inorganic pigments
- Document Type:
- Application
- Product Catalog Number:
- Multiple
- Product Catalog Name:
- Multiple
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Cobalt chloride decreases EC-SOD expression through intracellular ROS generation and p38-MAPK pathways in COS7 cells.
- It is known that cells suffer a chronic hypoxic condition during the development of proximal tubulointerstitial disease. However, it is accepted that extracellular-superoxide dismutase (EC-SOD) protects the cells from oxidative stress. The purpose of this study was to elucidate the regulation of EC-SOD expression in cells under hypoxia. The results show that the expressions of EC-SOD mRNA and protein in cobalt chloride (CoCl(2))-treated COS7 cells decreased in a dose- and time-dependent manner, whereas the expressions of other SOD isoforms (Cu/Zn-SOD and Mn-SOD) were not changed. The down-regulation of EC-SOD mRNA was suppressed by pre-treatment with the antioxidant trolox and the p38 mitogen-activated protein kinase (p38-MAPK) inhibitor SB203580. It is concluded that the expression of EC-SOD is decreased through ROS and p38-MAPK signalling cascades and that the down-regulation of EC-SOD leads to a decrease in the resistance to oxidative stress of COS7 cells under hypoxia induced by CoCl(2).
- Document Type:
- Reference
- Product Catalog Number:
- CT01
- Product Catalog Name:
- MTT Cell Growth Assay Kit
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Cobalt in waste water from the production and casting of non-ferrous metals
- Document Type:
- Application
- Product Catalog Number:
- Multiple
- Product Catalog Name:
- Multiple
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Technical Data Sheet 100246 Platin/Cobalt color reference solution (Hazen 500) Certipur
- Document Type:
- Technical Information
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117244 - Certificate of Quality - Spectroquant Cobalt Cell Test / Cobalt-Küvettentest / Test en cubetas Cobalto
- Document Type:
- Certificate
- Product Catalog Number:
- 117244
- Product Catalog Name:
- Cobalt Cell Test
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117244 - Spectroquant Cobalt Cell Test
- Document Type:
- User Guide