The MOC (Mouse Oral Cancer) cell lines provide a syngeneic HNSCC cancer model that can be transplanted into C57BL/6 mice. These lines are important models for immune cell infiltration studies. The MOC lines have been utilized to compare and identify potential clinical scenarios that are applicable to human Oral
Squamous Cell Carcinoma. The MOC22 cell line was derived from primary tumors in a C57BL/6 WT mouse and shows indolent growth compared with the aggressive, metastatic MOC2 line.
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