Light Diagnostics™ products for infectious disease
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The effect of rapid respiratory viral diagnostic testing on antibiotic use in a children's hospital.
- Document Type:
- Reference
- Product Catalog Number:
- 3296
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Comparison of different tissue cultures for isolation and quantitation of influenza and parainfluenza viruses
- Document Type:
- Reference
- Product Catalog Number:
- 3296
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Hong Kong influenza in a neonatal unit.
- Document Type:
- Reference
- Product Catalog Number:
- 3296
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Influenza A and B virus infection in infants and young children during the years 1957-1976
- Document Type:
- Reference
- Product Catalog Number:
- 3296
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Patterns of illness in the highly febrile young child: epidemiologic, clinical, and laboratory correlates.
- Three hundred one episodes of fever greater than or equal to 103 F were documented in 375 infants and young children observed in a comprehensive care clinic during the period October 1974 to October 1978. Of such highly febrile illnesses 79% were accompanied by respiratory tract signs or symptoms, 7% by disease at a site other than the respiratory tract, and 22% of illnesses had no localizing signs or symptoms. Viral cultures were obtained from the respiratory tract in 178 cases and were positive in 68: 57/134 from respiratory illness; 2/4 from illness at sites other than the respiratory tract; and 9/40 in children without localizing disease. Bacterial cultures of the upper respiratory tract were obtained in 191 illnesses, but the overall rate of isolation of Haemophilus influenzae, Streptococcus pneumoniae and group A streptococci (46%) did not differ from that in a group of well children (39%). Bacterial cultures of the blood were obtained in 89 patients with fever greater than or equal to 103 F and in an additional 41 children with lower temperatures. Nine children had documented systemic bacterial disease (eight positive blood cultures and one positive CSF). The rate of clinically apparent systemic bacterial disease in these otherwise normal infants was one bacteremic episode per 94 years of child care.
- Document Type:
- Reference
- Product Catalog Number:
- 3296
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Comparison of polyurethane foam to nylon flocked swabs for collection of secretions from the anterior nares in performance of a rapid influenza virus antigen test in a pe ...
- Rapid antigen testing of upper respiratory secretions collected with various swab types is often utilized for laboratory diagnoses of influenza virus infection. There are limited data on the effects of swab composition on test performance. This study compared the performance of the Quidel QuickVue Influenza A+B test on secretions from the anterior nares when a polyurethane foam swab was used for collection to that when a nylon flocked swab was used for collection. One hundred subjects who presented to a pediatric emergency department with symptoms suggestive of an influenza virus infection were recruited for the study. Foam and flocked swabs of the anterior nares were obtained from separate nares of each subject before a posterior nasopharyngeal swab was collected and placed into viral transport medium. The QuickVue test was performed directly on each swab type, and the results were compared to the results of reverse transcription-PCR (RT-PCR), direct fluorescent antibody (DFA) test, and viral culture performed on the transport medium. RT-PCR alone and DFA combined with culture were utilized as separate gold standards. There were 56 cases of influenza detected by RT-PCR; the QuickVue test was positive for 40 foam and 30 flocked swabs, for sensitivities of 71% and 54%, respectively (P = 0.01). Similarly, there were 49 influenza cases detected by DFA and/or culture; the QuickVue test was positive for 38 foam and 30 flocked swabs, for sensitivities of 78% and 61%, respectively (P = 0.13). This study suggests that polyurethane foam swabs perform better than nylon flocked swabs for the collection of secretions from anterior nares in the Quidel QuickVue Influenza A+B test.
- Document Type:
- Reference
- Product Catalog Number:
- 3296
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Considerations of the risk of influenza in children and indications for prophylaxis
- Document Type:
- Reference
- Product Catalog Number:
- 3296
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Epidemic influenza myopathy in Cincinnati in 1977
- Document Type:
- Reference
- Product Catalog Number:
- 3296
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Type C influenza virus. I. Studies of the virus and its distribution.
- Document Type:
- Reference
- Product Catalog Number:
- 3296