400010
Caspase-1 Inhibitor I
IL-1β Converting Enzyme (ICE) Inhibitor I, Ac-YVAD-CHO, L-709049
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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A potent, specific, and reversible inhibitor of caspase-1 (Ki = 200 pM for human recombinant caspase-1), caspase-4, and caspase-5. Strongly inhibits anti-APO-1 induced apoptosis in L929-APO-1 cells.
| Alternatives | |
|---|---|
| 400012 | Caspase-1 Inhibitor II |
| 218790 | Caspase-1 Assay Kit, Colorimetric |
| 400019 | Caspase-1 Inhibitor V |
| 218791 | Caspase-1 Assay Kit, Fluorometric |
| Alternative products for Caspase-1 Inhibitor I | |
| 400012 | Caspase-1 Inhibitor II |
| 218790 | Caspase-1 Assay Kit, Colorimetric |
| 400019 | Caspase-1 Inhibitor V |
| 218791 | Caspase-1 Assay Kit, Fluorometric |
| 218746 | Caspase-1 Inhibitor VI |
| 400015 | Caspase-1 Inhibitor IV |
| Accessories for Caspase-1 Inhibitor I |
| Product information | |||
|---|---|---|---|
| Peptide Sequence | Ac-Tyr-Val-Ala-Asp-CHO | ||
| Form | White solid | ||
| Primary Target | caspase-1 , human recombinant | ||
| Primary Target Ki | 200 pM | ||
| Secondary target | caspase-4, caspase-5 | ||
| Molar mass | 492.5 | ||
| Protect from Light | Yes | ||
| Reversible | Yes | ||
| Purity | ≥95% by TLC | ||
| Solubility | DMSO or H2O | ||
| Chemical formula | C23H32N4O8 | ||
| CAS number | 143313-51-3 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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