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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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A highly selective, competitive, cell-permeable, and irreversible inhibitor of caspase-1, caspase-4, and caspase-5. Inactivates the enzyme with a rate limited by diffusion and is relatively inert toward other bionucleophiles such as glutathione, making it an excellent candidate for in vivo studies of enzyme inhibition.
| Alternatives | |
|---|---|
| 400010 | Caspase-1 Inhibitor I |
| 218746 | Caspase-1 Inhibitor VI |
| 400012 | Caspase-1 Inhibitor II |
| 400019 | Caspase-1 Inhibitor V |
| Alternative products for Caspase-1 Inhibitor IV | |
| 400010 | Caspase-1 Inhibitor I |
| 218746 | Caspase-1 Inhibitor VI |
| 400012 | Caspase-1 Inhibitor II |
| 400019 | Caspase-1 Inhibitor V |
| Accessories for Caspase-1 Inhibitor IV |
| Product information | |||
|---|---|---|---|
| Peptide Sequence | Ac-Tyr-Val-Ala-Asp-AOM (AOM = 2,6-dimethylbenzoyloxymethyl ketone) | ||
| Form | White solid | ||
| Primary Target | caspase-1 | ||
| Secondary target | caspase-4, caspase-5 | ||
| Molar mass | 654.7 | ||
| Protect from Moisture | Yes | ||
| Cell permeable | Yes | ||
| Purity | ≥96% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C33H42N4O10 | ||
| CAS number | 154674-81-4 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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