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Optimization for Virus Safety
Step 3
Producing protein at the lowest cost per gram requires that you design and implement a consistent, well-defined virus strategy and optimization process. Achieving these goals also saves you time and materials and maximizes product recovery.Optimizing a virus filtration process involves evaluating the effect of a variety of process parameters to arrive at conditions that will ensure a robust, consistent, economical, and scalable operation.
For more than 20 years, Merck has been working side-by-side with industry-leading researchers and manufacturers helping them achieve the lowest possible cost for unit operations by successfully tackling some of the same challenges you are facing, such as:
- How do I prevent costly product dilutions?
- How do avoid costly buffer changes?
- What process steps can I combine or streamline without compromising product purity?
- What filtration methods will deliver the best results without locking me into a specific process?
Merck can help you achieve your goals at every step of the virus clearance operation by working with you to:
- Minimize your processing time
- Maximize product recovery
- Maximize your LRV
Are you leveraging the full resources of Merck?
Contact the Viresolve® Team to learn more about how we can help.
Related Resources
- Viral Clearance Validation Services
- Measurement of Pore Size Distribution and Prediction of Membrane Filter Virus Retention using Liquid-Liquid Porometry
- Viral Safety Assurance: Prevent, Detect, Remove
- Viresolve® Pro Virus Filtration Solution
- Mobius® FlexReady for Virus
- Provantage® Virus Validation Services
