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About This Item
Linear Formula:
C2H5CH(CH3)CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-798-2
MDL number:
Beilstein/REAXYS Number:
1721792
Product Name
L-Isoleucine, reagent grade, ≥98% (HPLC)
grade
reagent grade
Quality Level
assay
≥98% (HPLC)
form
powder
color
white
mp
288 °C (dec.) (lit.)
solubility
1 M NH4OH: 50 mg/mL
application(s)
detection
SMILES string
CC[C@H](C)[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1
InChI key
AGPKZVBTJJNPAG-WHFBIAKZSA-N
Application
L-Isoleucine has been used in capillary feeder (CAFE) assay in a study to determine the consumption of amino acids by Drosophila melanogaster. It has also been used as one of the components of an amino acid mixture, which is used as a supplement for synthetic complete (SC) media.
Biochem/physiol Actions
L-Isoleucine is an isomer of L-leucine and is an essential amino acid. It is synthesized from threonine and is a branched-chain hydrophobic amino acid.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Mated Drosophila melanogaster females consume more amino acids during the dark phase
Shun U
PLoS ONE (2017)
Conversion of ammonia or urea into essential amino acids,L-leucine,L-valine, andL-isoleucine using artificial cells containing an immobilized multienzyme system and dextran-NAD+
Applied Biochemistry and Biotechnology, 26 (1990)
Amino Acid Biosynthesis Is Regulated by Feedback Inhibition
Biochemistry (5th Edition) null