Cellvento® CHO media have been developed for use with CHO suspension cell types such as CHO-S, CHO-DHFR- , CHO-K1, CHO-GS and CHOZN® cells, but may also be suitable for other cell lines. Available in powder and compacted forms, Cellvento® CHO formulations are chemically defined, of non-animal origin and lead to superior cell growth and productivity in batch, fed-batch or perfusion applications.
For fed-batch processes we aim to reduce the complexity of workflows by offering highly concentrated and one-part pH neutral feeds, allowing for a reduction in volume of feed added to replenish depleted nutrients, thereby increasing product yield. Highly concentrated, compacted format, easy to hydrate and product stability even at room temperature through Cellvento® ModiFeed Prime COMP allow for streamlined workflows.
Recommended basal media combinations are Cellvento® CHO media or EX-CELL® Advanced CHO Fed-batch medium as described within the product detail pages.
Cellvento® 4CHO-X has been designed to support high growth and viability, thus increasing cell biomass for cryopreservation or inoculation of another bioreactor. Cellvento® 4CHO-X supports seed train intensification at N-1 in perfusion, reaching robust growth at low CSPRs.
|Use and Application||CHO-S Cell Lines||CHO-DHFR- and Slow Growing Cell Lines||CHO-K1 Cell Lines||CHOZN® Cell Lines|
|High concentrated single feed||Cellvento® ModiFeed Prime COMP|
|Fed-batch system with high concentrated single feed||Cellvento® 4CHO COMP Medium|
|Cellvento® 4Feed COMP|
|Enhanced Seed Train - N-1 Perfusion||Cellvento® 4CHO-X COMP
|Growth Media for Batch||Cellvento® CHO-110 Medium|
|Production Media and Companion Feeds for Fed-Batch with Cys/Tyr supplementation||Cellvento® CHO-200 Medium||Cellvento® CHO-210 Medium||Cellvento® CHO-220 Medium|
|Cellvento® Feed-200||Cellvento® Feed-210||Cellvento® Feed-220|