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Merck

W247804

Farnesol

mixture of isomers, ≥95%, stabilized, FG

Synonyme(s) :

3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol

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A propos de cet article

Formule linéaire :
(CH3)2C=CHCH2CH2C(CH3)=CHCH2CH2C(CH3)=CHCH2OH
Numéro CAS:
4602-84-0
Poids moléculaire :
222.37
FEMA Number:
2478
Council of Europe no.:
78
UNSPSC Code:
12164502
PubChem Substance ID:
24901122
Flavis number:
2.029
EC Number:
225-004-1
NACRES:
NA.21
MDL number:
MFCD00002918
Beilstein/REAXYS Number:
1763926
Organoleptic:
fresh; floral; sweet
Grade:
FG, Halal, Kosher
Biological source:
synthetic
Food allergen:
no known allergens

Principaux documents

Voir toute la documentation
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SMILES string

C/C(CC/C=C(C)/CCC=C(C)C)=C\CO

InChI

1S/C15H26O/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11,16H,5-6,8,10,12H2,1-4H3/b14-9+,15-11+

InChI key

CRDAMVZIKSXKFV-YFVJMOTDSA-N

biological source

synthetic

grade

FG, Halal, Kosher

reg. compliance

EU Regulation 1334/2008 & 178/2002, FDA 21 CFR 117, FDA 21 CFR 172.515

assay

≥95%

contains

α-tocopherol (synthetic stabilizer)

may contain

≤50 ppm hexane

refractive index

n20/D 1.489 (lit.)

bp

149 °C/4 mmHg (lit.)

density

0.886 g/mL at 20 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

fresh; floral; sweet

Quality Level

300, 400

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Catégories apparentées

Application


  • Farnesol repurposing for prevention and treatment of Acinetobacter baumannii biofilms.: This article explores the efficacy of repurposing farnesol for preventing and treating biofilms caused by Acinetobacter baumannii, highlighting its potential as an antibacterial agent (Tan et al., 2024).

  • Methyl-Jasmonate Functions as a Molecular Switch Promoting Cross-Talk between Pathways for the Biosynthesis of Isoprenoid Backbones Used to Modify Proteins in Plants.: This study investigates the role of methyl-jasmonate in regulating the biosynthesis of isoprenoid backbones, which are crucial for post-translational modification of proteins in plants and may involve farnesol as an intermediate or by-product (Chevalier et al., 2024).

  • Repurposing Farnesol for Combating Drug-Resistant and Persistent Single and Polymicrobial Biofilms.: This article discusses the potential of repurposing farnesol to combat drug-resistant and persistent biofilms, demonstrating its utility in enhancing antibiotic efficacy and addressing antimicrobial resistance (Tan et al., 2024).

Biochem/physiol Actions

Taste at 10 ppm

Other Notes

Natural occurrence: Apricot, orange peel and oil, grapefruit juice, cloves, ginger thyme beef, whiskey basil, papaya, anise seed and balsam of Peru.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1

Classe de stockage

10 - Combustible liquids

wgk

WGK 2

flash_point_f

311.0 °F - closed cup

flash_point_c

155 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificats d'analyse (COA)

Lot/Batch Number
SHBT1755
SHBS5506
SHBR7460
SHBP5185
SHBN6780

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

E Fayard et al.
Current opinion in lipidology, 12(2), 113-120 (2001-03-27)
Cholesterol and bile acid metabolism is tightly controlled by nuclear receptors. The liver X receptor, an oxysterol-activated nuclear receptor, limits cholesterol accumulation in the body both by stimulating reverse cholesterol transport and by inhibiting intestinal cholesterol absorption. The liver X
Phillip A Lichtor et al.
Nature chemistry, 4(12), 990-995 (2012-11-24)
Selectivity in the catalytic functionalization of complex molecules is a major challenge in chemical synthesis. The problem is magnified when there are several possible stereochemical outcomes and when similar functional groups occur repeatedly within the same molecule. Selective polyene oxidation
N Charette et al.
Cell death & disease, 4, e471-e471 (2013-01-26)
Ras activation is a frequent event in human hepatocarcinoma that may contribute to resistance towards apoptosis. Salirasib is a ras and mTOR inhibitor that induces a pro-apoptotic phenotype in human hepatocarcinoma cell lines. In this work, we evaluate whether salirasib
Efrat Mashiach-Farkash et al.
Oncotarget, 3(6), 629-639 (2012-07-11)
Neurofibromin regulates cell motility via three distinct GTPase pathways acting through two different domains, the Ras GTPase-activating protein-related domain (GRD) and the pre-GRD domain. First, the GRD domain inhibits Ras-dependent changes in cell motility through the mitogen activated protein cascade.
Najla Nasr et al.
Blood, 120(4), 778-788 (2012-06-09)
Macrophages are key target cells for HIV-1. HIV-1(BaL) induced a subset of interferon-stimulated genes in monocyte-derived macrophages (MDMs), which differed from that in monocyte-derived dendritic cells and CD4 T cells, without inducing any interferons. Inhibition of type I interferon induction
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