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46158

Dapsone

VETRANAL®, analytical standard

Synonyme(s) :

Sulfone de 4-aminophényle, DDS

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A propos de cet article

Formule linéaire :
(H2NC6H4)2SO2
Numéro CAS:
80-08-0
Poids moléculaire :
248.30
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757089
EC Number:
201-248-4
Beilstein/REAXYS Number:
788055
MDL number:
MFCD00007887
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grade

analytical standard

Quality Level

200

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

175-177 °C (lit.)

application(s)

cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

format

neat

SMILES string

Nc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2

InChI

1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2

InChI key

MQJKPEGWNLWLTK-UHFFFAOYSA-N

General description

Dapsone is a synthetic antibiotic belonging to the class of sulfonamides, which show inhibitory action against most gram-positive and many gram-negative organisms.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

Dapsone may be used as an analytical reference standard for the quantification of the analyte in animal samples and pharmaceutical formulations using different analytical techniques
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 1B - STOT RE 2 - STOT SE 2

target_organs

Blood, Blood,spleen,Liver

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
BCCJ3740
BCBX0187

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A spectrophotometric method for the determination of metoclopramide HCl and dapsone
Revanasidadappa D.H and Manju B
Journal of Pharmaceutical and Biomedical Analysis, 25(3-4), 631-637 (2001)
C Curti et al.
European journal of medicinal chemistry, 42(6), 880-884 (2007-02-27)
An original one-pot microwave reaction was developed for the synthesis of sulfone derivatives as new potent antimicrobial agents. This eco-friendly methodology conducted in 30min led to desired products with good yields. The sulfones (4a and 4b) were obtained via the
Determination of sulfonamides in animal tissues using cation exchange reversed phase sorbent for sample cleanup and HPLC-DAD for detection.
Hela W, et al.
Food Chemistry, 83(4), 601-608 (2003)
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