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Merck

A1330000

Acide L-aspartique

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Acide (S)-(+)-aminosuccinique, Acide (S)-aminobutanedioïque

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A propos de cet article

Formule linéaire :
HO2CCH2CH(NH2)CO2H
Numéro CAS:
Poids moléculaire :
133.10
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1723530
eCl@ss:
32160406
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grade

pharmaceutical primary standard

API family

aspartic acid

manufacturer/tradename

EDQM

mp

>300 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

N[C@@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

CKLJMWTZIZZHCS-REOHCLBHSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Aspartic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Principal neurotransmetteur de l'excitation synaptique rapide.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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M J Collins et al.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 354(1379), 51-64 (1999-03-26)
The increase in proportion of the non-biological (D-) isomer of aspartic acid (Asp) relative to the L-isomer has been widely used in archaeology and geochemistry as a tool for dating. the method has proved controversial, particularly when used for bones.
Stefanie Ritz-Timme et al.
Ageing research reviews, 1(1), 43-59 (2002-06-01)
Aspartic acid racemization (AAR) represents one of the major types of non-enzymatic covalent modification that leads to an age-dependent accumulation of abnormal protein in numerous human tissues. In vivo racemization is an autonomic process during the "natural" ageing of proteins
R A Azevedo et al.
Amino acids, 30(2), 143-162 (2006-03-10)
Aspartate is the common precursor of the essential amino acids lysine, threonine, methionine and isoleucine in higher plants. In addition, aspartate may also be converted to asparagine, in a potentially competing reaction. The latest information on the properties of the