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Merck

B0070000

Bacampicillin hydrochloride

European Pharmacopoeia (EP) Reference Standard

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A propos de cet article

Formule empirique (notation de Hill) :
C21H27N3O7S · HCl
Numéro CAS:
37661-08-8
Poids moléculaire :
501.98
MDL number:
MFCD11215256
UNSPSC Code:
41116107
NACRES:
NA.24

Principaux documents

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SMILES string

S1[C@H]2N([C@H](C1(C)C)C(=O)OC(OC(=O)OCC)C)C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3.[Cl-].[H+]

InChI

1S/C21H27N3O7S.ClH/c1-5-29-20(28)31-11(2)30-19(27)15-21(3,4)32-18-14(17(26)24(15)18)23-16(25)13(22)12-9-7-6-8-10-12;/h6-11,13-15,18H,5,22H2,1-4H3,(H,23,25);1H/t11?,13-,14-,15+,18-;/m1./s1

InChI key

IWVTXAGTHUECPN-ANBBSHPLSA-N

grade

pharmaceutical primary standard

API family

bacampicillin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Catégories apparentées

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bacampicillin hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Certificats d'analyse (COA)

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Y Akimoto et al.
General pharmacology, 24(4), 895-898 (1993-07-01)
1. Ampicillin concentrations in cyst wall (wall) and cyst fluid (fluid) of radicular cyst and serum following a single oral administration of bacampicillin (equivalent to 500 mg of ampicillin) were measured by a paper disk method. 2. The mean peak
J Laurent et al.
Alimentary pharmacology & therapeutics, 15(11), 1787-1793 (2001-10-31)
Helicobacter pylori eradication rates in France after therapy with omeprazole, amoxicillin and clarithromycin are among the lowest in Europe. This study evaluated alternative eradication regimens. Helicobacter pylori-positive patients (n=323) with non-ulcer dyspepsia were randomized to receive one of four 1-week
H Saka et al.
Kokyu to junkan. Respiration & circulation, 40(11), 1105-1108 (1992-11-01)
To evaluate the effect of bacampicillin hydrochloride on fever following fiberoptic bronchoscopy and bronchography, we conducted multi-institutional randomized study. In bronchographic examinations, the rise of body temperatures in the bacampicillin group (0.82 +/- 0.13 degrees C: mean +/- SE) was
M Bogataj et al.
Journal of microencapsulation, 8(3), 401-406 (1991-07-01)
Eudragit E microspheres containing bacampicillin hydrochloride were prepared by solvent evaporation and solvent extraction methods. Three different systems of solvents were used: methyl acetate, acetone and methanol/liquid paraffin. The success of the procedures depended mostly on the lipophilicity of the
G Reid et al.
Scandinavian journal of infectious diseases, 22(1), 43-47 (1990-01-01)
Specimens were examined from 70 female presenting with urinary tract infection. 50 patients were randomly treated with 7 days amoxicillin or bacampicillin and another 20 randomly received amoxicillin or enoxacin. Effective clearance of the infections was achieved with each antibiotic
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