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Merck

B0600000

Benzocaine

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

4-Aminobenzoic acid ethyl ester, Ethyl 4-aminobenzoate

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A propos de cet article

Formule empirique (notation de Hill) :
C9H11NO2
Numéro CAS:
94-09-7
Poids moléculaire :
165.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329773120
MDL number:
MFCD00007892
Beilstein/REAXYS Number:
638434

Principaux documents

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Nom du produit

Benzocaine, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3

SMILES string

CCOC(=O)c1ccc(N)cc1

InChI key

BLFLLBZGZJTVJG-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

benzocaine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Catégories apparentées

Application

Benzocaine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

233.6 °F

flash_point_c

112 °C

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

L F Rodriguez et al.
The Annals of pharmacotherapy, 28(5), 643-649 (1994-05-01)
To report a case of benzocaine-induced inethemoglobinemia and present a review of the related literature. An 83-year-old man received benzocaine topical anesthesia 600 mg prior to intubation for resection of a thyroid adenoma. The patient became severely cyanotic after induction
Benzocaine-induced methemoglobinemia in the pediatric population.
Jodi Lehr et al.
Journal of pediatric nursing, 27(5), 583-588 (2012-07-24)
Stephan Warnke et al.
Journal of the American Chemical Society, 137(12), 4236-4242 (2015-03-12)
The immediate environment of a molecule can have a profound influence on its properties. Benzocaine, the ethyl ester of para-aminobenzoic acid that finds an application as a local anesthetic, is found to adopt in its protonated form at least two
L A Linares et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 18(3), 267-269 (1990-07-01)
Methemoglobinemia is a condition in which more than 2% of the hemoglobin of the blood has been oxidized to the ferric form, a molecule which is incapable of binding oxygen or carbon dioxide. Clinically, the patient appears lethargic, cyanotic, and
H A Cooper
Southern medical journal, 90(9), 946-948 (1997-09-26)
Acute methemoglobinemia is a medical emergency that can rapidly become fatal. A substantial number of drugs, including topical preparations, can precipitate this condition. I report a rare example of severe, acute methemoglobinemia caused by oropharyngeal anesthesia with topical benzocaine spray
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