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C3090000

Cyclizine hydrochloride

Name: Cyclizine hydrochloride
Brand: SIAL

(European Pharmacopoeia (EP) Reference Standard)

Synonyme(s) :

1-Benzhydryl-4-methylpiperazine hydrochloride, Marezine hydrochloride

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A propos de cet article

Formule empirique (notation de Hill) :

C₁₈H₂₂N₂ · HCl

Numéro CAS:

303-25-3

Poids moléculaire :

302.84

MDL number:

MFCD00023293

UNSPSC Code:

41116107

NACRES:

NA.24

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Propriétés

grade

pharmaceutical primary standard

API family

cyclizine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Cl-].[N+H]1(CCN(CC1)C(c3ccccc3)c2ccccc2)C

InChI

1S/C18H22N2.ClH/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18H,12-15H2,1H3;1H

InChI key

UKPBEPCQTDRZSE-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cyclizine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Differential thermodynamic driving force of first- and second-generation antihistamines to determine their binding affinity for human H1 receptors.

Shigeru Hishinuma et al.

Biochemical pharmacology, 91(2), 231-241 (2014-07-30)

Differential binding sites for first- and second-generation antihistamines were indicated on the basis of the crystal structure of human histamine H1 receptors. In this study, we evaluated differences between the thermodynamic driving forces of first- and second-generation antihistamines for human