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Merck

M1650000

Méthyl 4-hydroxybenzoate, 4-hydroxybenzoate de méthyle

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Ester méthylique d’acide p-hydroxybenzoïque, NIPAGIN, Parahydroxybenzoate de méthyle

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A propos de cet article

Formule linéaire :
HOC6H4CO2CH3
Numéro CAS:
Poids moléculaire :
152.15
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
509801
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InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

SMILES string

COC(=O)c1ccc(O)cc1

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

parabens

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for use according to European Pharmacopoeia for the preparation of the below-given solutions:
  • Reference solutions (a) and (b) in the identification, testing for related substances, and assay of methyl parahydroxybenzoate and sodium methyl parahydroxybenzoate, according to the monographs 0409 and 1262
  • Reference solution (c) for the testing of related substances in nifuroxazide using liquid chromatography (2.2.29), according to the monograph 1999
  • Reference solution (b) in the identification of sodium ethyl parahydroxybenzoate using thin-layer chromatography (General text 2.2.27), according to the monograph 2134

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Environment

hcodes

Hazard Classifications

Aquatic Chronic 2

wgk

WGK 1

flash_point_f

334.4 °F

flash_point_c

168 °C

Classe de stockage

11 - Combustible Solids


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Consulter la Bibliothèque de documents

Sodium Ethyl Parahydroxybenzoate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3816-3817 (2017)
Sodium Methyl Parahydroxybenzoate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3830-3831 (2017)
Nifuroxazide
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3363-3364 (2017)
Methyl parahydroxybenzoate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 6180-6181 (2022)
Ismail I Hewala et al.
Talanta, 88, 623-630 (2012-01-24)
Simple methods for HPTLC peak purity assessment and identification of the HPTLC peaks were presented. The spectrodensitograms - selected at different time intervals across the elution time of the HPTLC peak - were extracted and digital algorithms for manipulating the

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