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Merck

PHR1122

2-Phényléthanol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

β-PEA, Alcool 2-phényléthylique, Benzyl carbinol, PEA

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A propos de cet article

Formule linéaire :
C6H5CH2CH2OH
Numéro CAS:
Poids moléculaire :
122.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-456-2
Beilstein/REAXYS Number:
1905732
MDL number:
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InChI key

WRMNZCZEMHIOCP-UHFFFAOYSA-N

InChI

1S/C8H10O/c9-7-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2

SMILES string

OCCc1ccccc1

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1533250

vapor density

4.21 (vs air)

vapor pressure

1 mmHg ( 58 °C)

API family

phenylethyl alcohol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.5317 (lit.)

bp

219-221 °C/750 mmHg (lit.)

mp

−27 °C (lit.)

density

1.020 g/mL at 20 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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General description

Phenylethyl alcohol, is a primary aromatic alcohol of high boiling point, having a characteristic rose-like odor. It presents organoleptic properties and impacts the quality of the wine, distilled beverages, and fermented foods. It shows its presence in fresh beer and is responsible for the rose-like odor of well-ripened cheese. It is commercially and industrially an important flavor and is a component of a variety of foodstuffs such as ice cream, gelatin, candy, pudding, chewing gum, and non-alcoholic beverages. It is formed by yeasts during fermentation of alcohols either by decomposition of L-phenylalanine or metabolism of sugar substrates.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Phenylethyl alcohol may be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations by spectrophotometric and chromatographic techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3266 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

215.6 °F - closed cup

flash_point_c

102 °C - closed cup


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Phenylethyl alcohol (PEA) application slows fungal growth and maintains aroma in strawberry
Mo EK and Sung CK
Postharvest biology and technology, 45(2), 234-239 (2007)
Determination of phenylethyl alcohol by reversed-phase high-performance liquid chromatography (RP-HPLC) in Budesonide nasal spray
Hosseini R, et al.
African Journal of Pure and Applied Chemistry, 9(5), 81-90 (2015)
Breeding of brewing yeast producing a large amount of ?-phenylethyl alcohol and ?-phenylethyl acetate
Fukuda K, et al.
Agricultural and Biological Chemistry, 54(1), 269-271 (1990)
Simultaneous Estimation of Fluticasone propionate, Azelastine Hydrochloride, Phenylethyl alcohol and Benzalkonium chloride by RP-HPLC Method in Nasal spray preparations
Rao KLN, et al.
International Journal of Research in Pharmaceutical Sciences, 1(4), 473-480 (2010)
Production of 2?Phenylethyl Alcohol by Kluyveromyces marxianus.
Fabre CE, et al.
Biotechnology Progress, 14(2), 270-274 (1998)

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