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Merck

PHR1130

D-gluconate de potassium

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Acide D-gluconique potassium salt, Acide 2,3,4,5,6-pentahydroxycaproïque potassium salt

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A propos de cet article

Formule empirique (notation de Hill) :
C6H11KO7
Numéro CAS:
299-27-4
Poids moléculaire :
234.25
NACRES:
NA.24
E Number:
E577
PubChem Substance ID:
329823151
UNSPSC Code:
41116107
EC Number:
206-074-2
MDL number:
MFCD00064211
Beilstein/REAXYS Number:
3919448

Principaux documents

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InChI

1S/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1

InChI key

HLCFGWHYROZGBI-JJKGCWMISA-M

SMILES string

[K+].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1550001

API family

potassium gluconate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

183 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Catégories apparentées

General description

Potassium Gluconate is a potassium salt of gluconic acid. It is a commonly administered nutrient supplement form of potassium.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Potassium Gluconate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7151in the slot below. This is an example certificate only and may not be the lot that you receive.

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificats d'analyse (COA)

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Potassium Gluconate
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 41(6), 3590-3590 (2018)
Herb, nutrient, and drug interactions: clinical implications and therapeutic strategies.
Stargrove MB, et al.
Herb, Nutrient, and Drug Interactions: Clinical Implications and Therapeutic Strategies (2008)
Jeffrey E Nowak et al.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 13(5), e323-e329 (2012-07-05)
We previously demonstrated that altered zinc homeostasis is an important feature of pediatric sepsis, thus raising the possibility of zinc supplementation as a therapeutic strategy in sepsis. Herein, we tested the hypothesis that prophylactic zinc supplementation would be beneficial in
Michael T Rose et al.
Planta, 236(4), 959-973 (2012-04-25)
Plants are routinely subjected to multiple environmental stresses that constrain growth. Zinc (Zn) deficiency and high bicarbonate are two examples that co-occur in many soils used for rice production. Here, the utility of metabolomics in diagnosing the effect of each
Ubaid H Shah et al.
Clinical nutrition (Edinburgh, Scotland), 32(2), 193-199 (2012-09-18)
Acute lower respiratory infections are the most frequent illnesses globally in children less than 5 years old. The aim of this randomized double blind controlled trial is to assess the effectiveness of zinc gluconate supplementation for 2 months period compared
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