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Merck

PHR1266

Acesulfame K

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Acesulfame potassium salt, 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide potassium salt

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A propos de cet article

Formule empirique (notation de Hill) :
C4H4KNO4S
Numéro CAS:
Poids moléculaire :
201.24
NACRES:
NA.24
E Number:
E950
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
259-715-3
MDL number:
Beilstein/REAXYS Number:
3637857
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. A0070000, traceable to USP 1002505

API family

acesulfame

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

[K+].CC1=CC(=O)[N-]S(=O)(=O)O1

InChI

1S/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6);/q;+1/p-1

InChI key

WBZFUFAFFUEMEI-UHFFFAOYSA-M

General description

Acesulfame K is a synthetically prepared sulfonyl amide sweetener, widely used with sugar alcohols in food and beverage industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Acesulfame K may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using capillary zone electrophoresis and ion chromatography.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC1663 in the slot below. This is an example certificate only and may not be the lot that you receive.


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Classe de stockage

11 - Combustible Solids

wgk

WGK 1



Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents



Bitter taste receptors for saccharin and acesulfame K
The Journal of Neuroscience, 24(45), 10260-10265 (2004)
Biotechnology and Food Ingredients (1991)
Simultaneous determination of artificial sweeteners, preservatives, caffeine, theobromine and theophylline in food and pharmaceutical preparations by ion chromatography
Chen C-Q and Wang J
Journal of Chromatography A, 937(1-2), 57-64 (2001)