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Merck

PHR1305

Sodium dodecylbenzenesulfonate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Dodecylbenzenesulfonic acid sodium salt

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A propos de cet article

Formule linéaire :
CH3(CH2)11C6H4SO3Na
Numéro CAS:
Poids moléculaire :
348.48
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
246-680-4
Beilstein/REAXYS Number:
4171051
MDL number:
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InChI key

JHJUUEHSAZXEEO-UHFFFAOYSA-M

InChI

1S/C18H30O3S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-17-13-15-18(16-14-17)22(19,20)21;/h13-16H,2-12H2,1H3,(H,19,20,21);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCCc1ccc(cc1)S([O-])(=O)=O

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1623637

API family

sodium dodecylbenzenesulfonate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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General description

Sodium dodecylbenzenesulfonate, commonly known as sodium lauryl phenyl sulfonate, is a linear alkylbenzene sulfonate that belongs to the class of anionic surfactants. Generally, it is used as an emulsifier, detergent, solubilizer and wetting agent in pharmaceutical, personal care, home care and food products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Sodium dodecylbenzenesulfonate may be used as a pharmaceutical reference standard for the determination of the analyte in raw material, environmental samples, personal care and home care formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3264 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Classe de stockage

11 - Combustible Solids

wgk

WGK 2

flash_point_f

No data available

flash_point_c

No data available


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Simple and rapid determination of linear alkylbenzene sulfonates by in-tube solid-phase microextraction coupled with liquid chromatography
Hirayama Y, et al.
Journal of Health Science, 52(3), 228-236 (2006)
Adsorption of linear alkyl benzene sulfonates on oil-water interface: Effects of Na+, Mg2+ and Ca2+ ions
Anachkov SE, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 466, 18-27 (2015)
Development of a method by HPLC to determine LAS and its application in anaerobic reactors
Duarte I, et al.
Journal of the Brazilian Chemical Society, 17(7), 1360-1367 (2006)
Determination of surfactant mixtures in shampoos and detergents by HPLC
Nakamura K and Morikawa Y
Journal of the American Oil Chemists' Society, 61(6), 1130-1135 (1984)
Amended safety assessment of dodecylbenzenesulfonate, decylbenzenesulfonate, and tridecylbenzenesulfonate salts as used in cosmetics
Becker LC, et al.
International Journal of Toxicology, 29, 288S-305S (2010)

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