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Merck

T0040800

Tenoxicam

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide

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A propos de cet article

Formule empirique (notation de Hill) :
C13H11N3O4S2
Numéro CAS:
59804-37-4
Poids moléculaire :
337.37
NACRES:
NA.24
PubChem Substance ID:
329826581
UNSPSC Code:
41116107
MDL number:
MFCD00083502

Principaux documents

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InChI

1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18)

SMILES string

O=C(NC1=NC=CC=C1)C2=C(O)C(SC=C3)=C3S(N2C)(=O)=O

InChI key

LZNWYQJJBLGYLT-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

tenoxicam

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Catégories apparentées

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Tenoxicam EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Non-steroidal antiinflammatory drug (NSAID) with comparatively low risk of renal or hepatic toxicity.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Michael H Bennett et al.
Anesthesia and analgesia, 111(3), 757-762 (2010-03-25)
Decompression illness (DCI) is caused by bubble formation in the blood or tissues after a reduction in ambient pressure. Clinically, DCI may range from a trivial illness to paralysis, loss of consciousness, cardiovascular collapse, and death. Recompression is the universally
Ebru Cubuk Demiralay et al.
Journal of separation science, 32(17), 2928-2936 (2009-08-08)
In this study, pK(a) values were determined by using the dependence of the capacity factor on the pH of the mobile phase for four ionizable substances, namely, tenoxicam, piroxicam, meloxicam, and naproxen (I.S.). The effect of the mobile phase composition
Michael H Bennett et al.
The Cochrane database of systematic reviews, 5(5), CD005277-CD005277 (2012-05-18)
Decompression illness (DCI) is due to bubble formation in the blood or tissues following the breathing of compressed gas. Clinically, DCI may range from a trivial illness to loss of consciousness, death or paralysis. Recompression is the universally accepted standard
Photoclinic. Fixed drug eruption.
Vitorino Modesto Santos et al.
Archives of Iranian medicine, 14(1), 71-72 (2011-01-05)
Marco Franco-Pérez et al.
The journal of physical chemistry. B, 115(46), 13593-13598 (2011-10-11)
The determination of the micro-equilibrium prototropic constants is often a tough task when the tautomeric ratio favors one of the species or when the chemical exchange is not slow enough to allow the quantitative detection of the tautomeric species. There
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