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Merck

Y0000012

Hymecromone impurity A

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Resorcinol, 1,3-Benzenediol

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A propos de cet article

Formule linéaire :
C6H4-1,3-(OH)2
Numéro CAS:
Poids moléculaire :
110.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
906905
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grade

pharmaceutical primary standard

vapor density

3.8 (vs air)

vapor pressure

1 mmHg ( 21.1 °C)

API family

hymecromone

autoignition temp.

1126 °F

manufacturer/tradename

EDQM

bp

178 °C/16 mmHg (lit.)

mp

109-112 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Oc1cccc(O)c1

InChI

1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H

InChI key

GHMLBKRAJCXXBS-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hymecromone impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 1 Oral - STOT SE 2 Oral

target_organs

Central nervous system,Blood, Respiratory system

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

260.6 °F - closed cup

flash_point_c

127 °C - closed cup



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50% resorcinol peel.
P G Karam
International journal of dermatology, 32(8), 569-574 (1993-08-01)
Resorcinol.
IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 3, 1119-1131 (1999-09-07)
Frank Welsch
International journal of toxicology, 27(1), 59-63 (2008-02-23)
Medical case reports published in the 20th century over the course of several decades show that resorcinol caused reversible adverse effects on the human thyroid gland (TG) manifested as hypothyroidism. Affected patients had ulcerating leg varicosities and underwent prolonged treatment