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Merck

RAB0369

Human MMP-7 ELISA Kit

on for cell culture supernatant

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A propos de cet article

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... MMP7(4316)
Input:
sample type cell culture supernatant(s)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 150 pg/mL
standard curve range: 0.137-100 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... MMP7(4316)

General description

The human MMP-7 ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-7 in cell culture supernatants. Matrix metalloproteinase-7 (MMP-7)/matrilysin is a small proteolytic enzyme. It secretes zinc- and calcium-dependent endopeptidase. It is expressed in normal endometrial, bronchial, ductal, skin glandular epithelial, urogenital, and gastrointestinal tissues. MMP-7 plays a key role in cell proliferation, migration, invasion, and apoptosis. Elevated expression of MMP-7 is seen in several cancers, such as esophageal, gastric, gallbladder, pancreatic, colorectal, bladder, ovarian, breast, lung, and melanoma.

Immunogen

Recombinant Human MMP7

Application

Human MMP-7 ELISA Kit has been used in ELISA to measure the recovery of the cancer biomarkers/MMP-7 in isothermally vitrified samples. It has also been used in ELISA to determine MMP7 concentrations in multiple myeloma (MM) cell culture supernatants.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Composants de kit également disponibles séparément

Réf. du produit
Description
FDS

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)FDS

  • RABSTOP3ELISA Stop Solution (Item I)FDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)FDS

  • RABWASH420X Wash Buffer (Item B)FDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Classe de stockage

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable


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Guobao Wang et al.
Arthritis & rheumatology (Hoboken, N.J.), 73(2), 265-275 (2020-09-07)
Flares of lupus nephritis (LN) are frequent and associated with impaired renal prognosis. One major management obstacle in LN flare is the lack of effective methods to identify at-risk patients earlier in their disease course. This study was undertaken to
Hai-Yang Liao et al.
Clinical biochemistry, 92, 9-18 (2021-03-14)
Matrix metalloproteinase-7 (MMP-7) is a small proteolytic enzyme that secretes zinc and calcium endopeptidases. It can degrade a variety of extracellular matrix substrates and other substrates and plays important regulatory roles in many human pathophysiological processes. Since its discovery, MMP-7
Ruth Eichner et al.
Nature medicine, 22(7), 735-743 (2016-06-14)
Immunomodulatory drugs (IMiDs), such as thalidomide and its derivatives lenalidomide and pomalidomide, are key treatment modalities for hematologic malignancies, particularly multiple myeloma (MM) and del(5q) myelodysplastic syndrome (MDS). Cereblon (CRBN), a substrate receptor of the CRL4 ubiquitin ligase complex, is
Kasturi Chatterjee et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(8), 4560-4572 (2018-03-21)
Endometriosis, characterized by extrauterine development of endometrial glands and stroma, is associated with increased risk of ovarian cancer development. In the present study, we investigated the role of matrix metalloproteinase-7 (MMP-7) on epithelial-mesenchymal transition (EMT) during ovarian endometriosis ( N
Vladimir Riabov et al.
Acta biomaterialia, 53, 389-398 (2017-02-06)
The immediate tissue microenvironment of implanted biomedical devices and engineered tissues is highly influential on their long term fate and efficacy. The creation of a long-term anti-inflammatory microenvironment around implants and artificial tissues can facilitate their integration. Macrophages are highly

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