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Merck

48670

N-Nitrosodimethylamine solution

certified reference material, 200 μg/mL in methanol

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A propos de cet article

Numéro CAS:
62-75-9
UNSPSC Code:
12352200
MDL number:
MFCD00002053
NACRES:
NA.24

Principaux documents

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SMILES string

N(N=O)(C)C

InChI

1S/C2H6N2O/c1-4(2)3-5/h1-2H3

InChI key

UMFJAHHVKNCGLG-UHFFFAOYSA-N

grade

certified reference material, TraceCERT®

agency

EPA TO-7

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

concentration

200 μg/mL in methanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

single component solution

storage temp.

2-30°C

Quality Level

300

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Catégories apparentées

General description

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosodimethylamine (NDMA) solution is commonly employed as a certified reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.

Application

N-Nitrosodimethylamine (NDMA) solution may be used as an analytical reference standard for the determination of nitrosamines in water liquid chromatography coupled to tandem mass spectrometry.

Analysis Note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with  ISO 17034  and  ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Classe de stockage

3 - Flammable liquids

wgk

WGK 3

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Determination of eight nitrosamines in water at the ng L- 1 levels by liquid chromatography coupled to atmospheric pressure chemical ionization tandem mass spectrometry
Ripolles, et al.
Analytica Chimica Acta, 702, 62-71 (2011)
Jin Woong Kim et al.
Journal of magnetic resonance imaging : JMRI, 53(2), 554-563 (2020-07-03)
Liver fibrosis is characterized by the excessive accumulation of extracellular matrix proteins. Electrical conductivity imaging at low frequency can provide novel contrast because the contrast mechanisms originate from the changes in the concentration and mobility of ions in the extracellular
Lactic acid bacteria directly degrade N-nitrosodimethylamine and increase the nitrite-scavenging ability in kimchi
Kim H-S, et al.
Food Control, 71, 101-109 (2017)
The role of Cu (II) in the reduction of N-nitrosodimethylamine with iron and zinc
Han Y, et al.
Chemosphere, 167, 171-177 (2017)
Man-Chun Huang et al.
Food chemistry, 138(1), 227-233 (2012-12-26)
A sensitive procedure, microwave-assisted extraction (MAE) coupled dispersive micro solid-phase extraction (D-μ-SPE), was developed to extract N-nitrosodimethylamine (NDMA) and other six volatile N-nitrosamines (NAms) from meat products. Parameters affecting the efficiency of MAE and D-μ-SPE were systematically investigated. For MAE
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