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Merck

1356916

USP

Lansoprazole

United States Pharmacopeia (USP) Reference Standard

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A propos de cet article

Formule empirique (notation de Hill) :
C16H14F3N3O2S
Numéro CAS:
103577-45-3
Poids moléculaire :
369.36
NACRES:
NA.24
PubChem Substance ID:
329750232
UNSPSC Code:
41116107
MDL number:
MFCD00866873

Principaux documents

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InChI

1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)

SMILES string

Cc1c(CS(=O)c2nc3ccccc3[nH]2)nccc1OCC(F)(F)F

InChI key

MJIHNNLFOKEZEW-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

lansoprazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... ATP4A(495), ATP4B(496)

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Catégories apparentées

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lansoprazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Lansoprazole Compounded Oral Suspension
  • Lansoprazole Delayed-Release Capsules

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Classe de stockage

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Lot/Batch Number

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A modified high-performance liquid chromatographic method for the analysis of pantoprazole sodium in pharmaceutical dosage forms using lansoprazole as internal standard.
Ashour, Safwan, and Soulafa Omar.
Arabian Journal of Chemistry, 1-6 (2011)
T Iwahi et al.
Antimicrobial agents and chemotherapy, 35(3), 490-496 (1991-03-01)
The activities of various types of antiulcer agents against Helicobacter pylori (formerly called Campylobacter pylori) strains were determined by an agar dilution method. Among the compounds tested, two benzimidazole proton pump inhibitors, lansoprazole (AG-1749) and omeprazole, were found to have
Hiroto Miwa et al.
Journal of gastroenterology and hepatology, 30(5), 834-841 (2015-01-07)
Non-erosive reflux disease (NERD) and functional dyspepsia (FD) share some common features, and the appropriateness of managing these diseases independently has been questioned. A post-hoc subgroup analysis of the LEGEND study was performed to compare demographics and treatment response between
Ken Haruma et al.
Internal medicine (Tokyo, Japan), 54(7), 695-701 (2015-04-04)
Although gastroesophageal reflux disease (GERD), a very common disorder worldwide, is considered to be a lifestyle disease, the pathogenic role of lifestyle factors and consequently the efficacy of lifestyle interventions, remains controversial. Lifestyle factors associated with GERD and the beneficial
Yasunobu Yamashita et al.
PloS one, 9(5), e97419-e97419 (2014-05-23)
Lansoprazole is a potent anti-gastric ulcer drug that inhibits gastric proton pump activity. We identified a novel function for lansoprazole, as an inducer of anti-oxidative stress responses in the liver. Gastric administration of lansoprazole (10-100 mg/kg) to male Wistar rats
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