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Merck

1601500

USP

Residual Solvent Class 2 - N,N-Dimethylformamide

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

N,N-Dimethylformamide solution

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A propos de cet article

Formule empirique (notation de Hill) :
C3H7NO
Numéro CAS:
Poids moléculaire :
73.09
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

N(C)(C)C=O

InChI

1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3

InChI key

ZMXDDKWLCZADIW-UHFFFAOYSA-N

General description

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Residual Solvent Class 2 - N,N-Dimethylformamide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup



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K Tanaka et al.
Sangyo igaku. Japanese journal of industrial health, 24(1), 3-12 (1982-01-01)
Industrial use of N, N-dimethylformamide (DMF) is increasing in recent years. The toxic properties of this substance are reviewed from the standpoint of industrial hygiene. Hepatotoxicity has been emphasized by many authors. Care should be taken against the skin absorption
Shengtao Ding et al.
Angewandte Chemie (International ed. in English), 51(37), 9226-9237 (2012-08-30)
Often used as a common solvent for chemical reations and utilized widely in industry as a reagent, N,N-dimethylformamide (DMF) has played an important role in organic synthesis for a long time. Numerous highly useful articles and reviews discussing its utilizations
Metabolism of N,N-dimethylformamide: key to the understanding of its toxicity.
A Gescher
Chemical research in toxicology, 6(3), 245-251 (1993-05-01)