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Merck

AB15552

Anti-AT1 Receptor Antibody

Chemicon®, from rabbit

別名:

Angiotensin II receptory type 1, AGTR1

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この商品について

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Species reactivity:
mouse, rat, human
Citations:
14
Technique(s):
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
Uniprot accession no.:
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製品名

Anti-AT1 Receptor Antibody, Chemicon®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat, human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... AGTR1(185)

関連するカテゴリー

Analysis Note

Control
Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.

Application

Anti-AT1 Receptor Antibody detects level of AT1 Receptor & has been published & validated for use in FC, IC, IH & WB.
Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism

Hormones & Receptors
Western blot: 1:200-1:500 using ECL on rat liver, rat kidney, mouse heart and mouse kidney lysate.
Immunohistochemistry on rat brain sections.
Immunocytochemistry: 1:100
Flow cytometry, indirect: 5-10 µg of antibody /1 x 106 cells
Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Recognizes AT1 Receptor (Angiotensin II receptory type 1, AGTR1).
The immunogen sequence is identical in canine.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Purified peptide from the N-terminus of human AT1 Receptor (Accession number P30556).

Physical form

Format: Purified
ImmunoAffinity Purified
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.05% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).

Preparation Note

Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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hcodes

Hazard Classifications

Aquatic Chronic 3

保管分類

11 - Combustible Solids

wgk

WGK 3


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Poisonous substance

pdsc

AB15552-200UL: + AB15552-50UL:

jan


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Francielle Graus-Nunes et al.
World journal of hepatology, 11(4), 359-369 (2019-05-23)
Obesity has been associated with hepatic overexpression of the renin-angiotensin system (RAS). To evaluate the action of two angiotensin II (ANGII) receptor blockers (losartan or telmisartan) on the modulation of local hepatic RAS and the resulting metabolic effects in a
null
Mehmet Hakan Ozdener et al.
Nutrients, 14(13) (2022-07-10)
In addition to the α, β, and γ subunits of ENaC, human salt-sensing taste receptor cells (TRCs) also express the δ-subunit. At present, it is not clear if the expression and function of the ENaC δ-subunit in human salt-sensing TRCs
Julius Benicky et al.
Cellular and molecular neurobiology, 32(8), 1353-1365 (2012-07-31)
Commercially available Angiotensin II AT1 receptor antibodies are widely employed for receptor localization and quantification, but they have not been adequately validated. In this study, six commercially available AT1 receptor antibodies were characterized by established criteria: sc-1173 and sc-579 from
Chien-Ning Hsu et al.
International journal of molecular sciences, 19(8) (2018-08-22)
Hypertension can originate from early-life adverse environmental in utero exposure to dexamethasone (DEX) or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Since DEX and TCDD are related to the aryl hydrocarbon receptor (AHR) signaling pathway, we examined whether resveratrol, an AHR modulator and antioxidant, could

グローバルトレードアイテム番号

カタログ番号GTIN
AB15552-200UL04053252471223

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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