03-5300
酪酸
SAJ special grade, ≥99.5%
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この商品について
化学式:
CH3CH2CH2COOH
CAS番号:
分子量:
88.11
PubChem Substance ID:
UNSPSC Code:
12352106
Beilstein/REAXYS Number:
906770
MDL number:
SMILES string
CCCC(O)=O
InChI key
FERIUCNNQQJTOY-UHFFFAOYSA-N
InChI
1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)
grade
SAJ special grade
vapor density
3.04 (vs air)
vapor pressure
0.43 mmHg ( 20 °C)
assay
≥99.5%
form
liquid
autoignition temp.
824 °F
expl. lim.
10 %
availability
available only in Japan
pH
2 (25 °C, 10 g/L), 3 (20 °C, 10 g/L)
pKa (20.7 °C)
4.9
bp
162 °C (lit.)
mp
−6-−3 °C (lit.)
density
0.964 g/mL at 25 °C (lit.)
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
保管分類
8A - Combustible corrosive hazardous materials
wgk
WGK 1
flash_point_f
167.0 °F
flash_point_c
75 °C
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
第4類:引火性液体 + 第三石油類 + 危険等級III + 水溶性液体
fsl
名称等を表示すべき危険物及び有害物
ishl_indicated
名称等を通知すべき危険物及び有害物
ishl_notified
03-5300-2-25G-J: + 03-5300-5-500ML-J:
jan
Ada Rephaeli et al.
International journal of cancer, 116(2), 226-235 (2005-04-01)
AN-7, a prodrug of butyric acid, induced histone hyperacetylation and differentiation and inhibited proliferation of human prostate 22Rv1 cancer cells in vitro and in vivo. In nude mice implanted with these cells, 50 mg/kg AN-7 given orally thrice a week
Hans G Cruz et al.
Nature neuroscience, 7(2), 153-159 (2004-01-28)
The rewarding effect of drugs of abuse is mediated by activation of the mesolimbic dopamine system, which is inhibited by putative anti-craving compounds. Interestingly, different GABA(B) receptor agonists can exert similarly opposing effects on the reward pathway, but the cellular
Svenja Plöger et al.
Annals of the New York Academy of Sciences, 1258, 52-59 (2012-06-27)
Butyrate production in the large intestine and ruminant forestomach depends on bacterial butyryl-CoA/acetate-CoA transferase activity and is highest when fermentable fiber and nonstructural carbohydrates are balanced. Gastrointestinal epithelia seem to use butyrate and butyrate-induced endocrine signals to adapt proliferation, apoptosis
Shomik Sengupta et al.
Journal of gastroenterology and hepatology, 21(1 Pt 2), 209-218 (2006-02-08)
Butyrate, the four-carbon fatty acid, is formed in the human colon by bacterial fermentation of carbohydrates (including dietary fiber), and putatively suppresses colorectal cancer (CRC). Butyrate has diverse and apparently paradoxical effects on cellular proliferation, apoptosis and differentiation that may
Carlo F M Welters et al.
Diseases of the colon and rectum, 45(5), 621-627 (2002-05-11)
Inflammation is a constant finding in the ileal reservoir of patients with an ileal pouch-anal anastomosis and is associated with decreased fecal concentrations of the short chain fatty acid butyrate, increased fecal pH, changes in fecal flora, and increased concentrations
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