01973
4-アミノ安息香酸
analytical standard
別名:
PABA, ビタミンBx, ビタミンH1
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この商品について
化学式:
H2NC6H4CO2H
CAS番号:
分子量:
137.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-753-0
Beilstein/REAXYS Number:
471605
MDL number:
SMILES string
Nc1ccc(cc1)C(O)=O
InChI
1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChI key
ALYNCZNDIQEVRV-UHFFFAOYSA-N
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
186-188 °C, 187-189 °C (lit.)
density
1.374 g/mL at 25 °C (lit.)
application(s)
cleaning products
cosmetics
environmental
food and beverages
personal care
format
neat
Quality Level
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Application
- 4-Aminobenzoic Acid (PABA) in Pharmaceutical Development: Recognized as a valuable biochemical research reagent, 4-aminobenzoic acid is extensively used in the synthesis of various pharmaceutical compounds. Its role as a building block in drug design is crucial for developing new therapeutic agents, particularly in the fields of dermatology and oncology (Clegg and Nichol, 2024).
- UV Protection Research: PABA is renowned for its UV-absorbing properties, making it a key ingredient in sunscreen formulations. Ongoing research evaluates its efficacy and safety, ensuring optimal protection against UV radiation and its potential role in preventing skin cancer (Wang et al., 2024).
- Enzyme Inhibitor Studies: As a nucleoside enzyme inhibitor, 4-aminobenzoic acid is pivotal in biochemical studies that explore the inhibition mechanisms of specific enzymes. These studies are fundamental for understanding disease pathways and developing enzyme-targeted therapies (Buch et al., 2024).
- Vitamin B10 Research: Also known as Vitamin B10, PABA is studied for its role in human nutrition and its therapeutic effects, including in the management of fibrotic skin disorders and hair growth promotion. Research continues to uncover the broader health benefits of this compound (Berto et al., 2024).
- High-Purity PABA for Laboratory Applications: In scientific research, high-purity 4-aminobenzoic acid is essential for conducting precise and controlled experiments, particularly in studies related to its pharmacological properties and its interaction with other biochemical substances in the body (Park et al., 2024).
Packaging
底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。
Other Notes
Ion Mobility: TWCCSN2 value of 133.2 Å2 [M+H]+
The collision cross section (CCS) measurement was provided by Waters Corporation, using the SYNAPT XS mass spectrometer.
For a description and overview of how ion mobility enables the measurement of the CCS of an ion visit ims.waters.com.
Further information on the SYNAPT XS mass spectrometer can be found on the IMS microsite and product webpage.
TWCCS measurements are expected to be within 2% of this reference value.
P/N 01973 is part of the Waters Extractables & Leachables UNIFI scientific library which can be downloaded from Waters Marketplace.
The collision cross section (CCS) measurement was provided by Waters Corporation, using the SYNAPT XS mass spectrometer.
For a description and overview of how ion mobility enables the measurement of the CCS of an ion visit ims.waters.com.
Further information on the SYNAPT XS mass spectrometer can be found on the IMS microsite and product webpage.
TWCCS measurements are expected to be within 2% of this reference value.
P/N 01973 is part of the Waters Extractables & Leachables UNIFI scientific library which can be downloaded from Waters Marketplace.
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 3
保管分類
11 - Combustible Solids
wgk
WGK 2
flash_point_f
339.8 °F - closed cup
flash_point_c
171 °C - closed cup
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
01973-100MG: + 01973-BULK: + 01973-VAR:
jan
L O Derewlany et al.
The Journal of pharmacology and experimental therapeutics, 269(2), 756-760 (1994-05-01)
The fetus is exposed to almost all of the substances found in the maternal circulation whether nutrients or foreign chemicals ("xenobiotics"). The main route of exposure is the placenta. The placenta is metabolically active toward xenobiotics and the nature of
L O Derewlany et al.
The Journal of pharmacology and experimental therapeutics, 269(2), 761-765 (1994-05-01)
Studies in our laboratory have shown that the N-acetylation activity of the human term placenta is a predominantly attributable to the NAT1 form of arylamine N-acetyltransferase (NAT). To further assess the acetylation capacity of the placenta, the N-acetylation of the
Shu-Ting Chen et al.
Journal of the American Society for Mass Spectrometry, 23(8), 1408-1418 (2012-06-08)
A strategy based on negative ion electrospray ionization tandem mass spectrometry and closed-ring labeling with both 8-aminopyrene-1,3,6-trisulfonate (APTS) and p-aminobenzoic acid ethyl ester (ABEE) was developed for linkage and branch determination of high-mannose oligosaccharides. X-type cross-ring fragment ions obtained from
Steven C Bremmer et al.
Chemical communications (Cambridge, England), 48(44), 5482-5484 (2012-04-28)
A modular system for detecting protease activity via enzyme-triggered gel formation is described. Protease-specific recognition sequences are utilized to achieve enzyme specificity. Artificial blood clotting is demonstrated by activating endogenous thrombin to trigger gelation in fibrinogen-deficient blood plasma.
Yoshihiko Tashiro et al.
Blood, 119(26), 6382-6393 (2012-05-11)
Plasminogen activator inhibitor-1 (PAI-1), an endogenous inhibitor of a major fibrinolytic factor, tissue-type plasminogen activator, can both promote and inhibit angiogenesis. However, the physiologic role and the precise mechanisms underlying the angiogenic effects of PAI-1 remain unclear. In the present
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