08267
アクリルアミド
certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
別名:
2-プロペンアミド, アクリル酸アミド
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この商品について
化学式:
CH2=CHCONH2
CAS番号:
分子量:
71.08
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
201-173-7
Beilstein/REAXYS Number:
605349
MDL number:
製品名
アクリルアミド, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
InChI
1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)
InChI key
HRPVXLWXLXDGHG-UHFFFAOYSA-N
SMILES string
NC(=O)C=C
grade
certified reference material
TraceCERT®
vapor density
2.45 (vs air)
vapor pressure
0.03 mmHg ( 40 °C)
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
bp
125 °C/25 mmHg (lit.)
mp
82-86 °C (lit.)
application(s)
cleaning products
cosmetics
environmental
food and beverages
personal care
format
neat
Quality Level
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Packaging
底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。
Application
- Advanced Synthesis Techniques: Acrylamide is utilized in the synthesis of acyl cyclopentaquinolinones, showcasing its versatility in heterocyclic scaffold construction and acyl group introduction, proving essential for organic synthesis in pharmaceutical research (Xue et al., 2024).
- Material Development for Energy Sectors: Acrylamide-based polymers are applied in developing temperature-sensitive materials for oil and gas drilling, highlighting its importance in creating responsive materials for challenging environments (Yang et al., 2024).
- Innovations in Polymer Science: The use of acrylamide in the numerical simulation of polyacrylamide hydrogel via thermally initiated frontal polymerization provides insights into the controlled synthesis of hydrogels, useful in biomedical applications (Yi et al., 2024).
- Health Impact Studies: Research includes acrylamide in studies examining the inhibition of harmful Maillard reaction products by polyphenols, relevant for understanding chronic diseases linked to dietary acrylamide (Ye et al., 2024).
General description
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Oral
target_organs
Peripheral nervous system
保管分類
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
280.4 °F - closed cup
flash_point_c
138 °C - closed cup
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
劇物
pdsc
第一種指定化学物質
prtr
名称等を表示すべき危険物及び有害物
ishl_indicated
名称等を通知すべき危険物及び有害物
ishl_notified
08267-BULK: + 08267-100MG:4548173346694 + 08267-VAR:
jan
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Arianna Rath et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(39), 15668-15673 (2013-09-11)
SDS/PAGE is universally used in biochemistry, cell biology, and immunology to resolve minute protein amounts readily from tissue and cell extracts. Although molecular weights of water-soluble proteins are reliably determined from their SDS/PAGE mobility, most helical membrane proteins, which comprise
Rusty L Montgomery et al.
EMBO molecular medicine, 6(10), 1347-1356 (2014-09-23)
Over the last decade, great enthusiasm has evolved for microRNA (miRNA) therapeutics. Part of the excitement stems from the fact that a miRNA often regulates numerous related mRNAs. As such, modulation of a single miRNA allows for parallel regulation of
Dietary acrylamide intake and the risk of colorectal cancer with specific mutations in KRAS and APC.
Janneke G F Hogervorst et al.
Carcinogenesis, 35(5), 1032-1038 (2014-01-09)
Acrylamide, a probable human carcinogen, is present in heat-treated carbohydrate-rich foods. Epidemiological studies have not shown a clear association between acrylamide intake and colorectal cancer (CRC) risk. This may be due to the molecular heterogeneity in colorectal tumors, which was
Franco Pedreschi et al.
Journal of the science of food and agriculture, 94(1), 9-20 (2013-08-14)
Acrylamide (AA) is known as a neurotoxin in humans and it is classified as a probable human carcinogen by the International Agency of Research on Cancer. AA is produced as by-product of the Maillard reaction in starchy foods processed at
Navid Bonakdar et al.
Experimental cell research, 331(2), 331-337 (2014-12-03)
Plectin is the prototype of an intermediate filament (IF)-based cytolinker protein. It affects cells mechanically by interlinking and anchoring cytoskeletal filaments and acts as scaffolding and docking platform for signaling proteins to control cytoskeleton dynamics. The most common disease caused
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