ログインで組織・契約価格をご覧ください。
サイズを選択してください
表示を変更する
この商品について
化学式:
CH3(CH2)10CON(CH3)CH2COOH
CAS番号:
分子量:
271.40
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
202-608-3
MDL number:
Beilstein/REAXYS Number:
1792084
製品名
N-ラウロイルサルコシン, purum p.a., ≥98.0% (GC)
description
anionic
Quality Level
grade
purum p.a.
assay
≥98.0% (GC)
mol wt
271.40 g/mol
technique(s)
protein quantification: suitable
impurities
≤0.2% water
ign. residue
≤0.1%
mp
45-50 °C
anion traces
chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤100 mg/kg
cation traces
Ca: ≤20 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤10 mg/kg, K: ≤70 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤20 mg/kg
functional group
amide, carboxylic acid
SMILES string
CCCCCCCCCCCC(=O)N(C)CC(O)=O
InChI
1S/C15H29NO3/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19/h3-13H2,1-2H3,(H,18,19)
InChI key
BACYUWVYYTXETD-UHFFFAOYSA-N
General description
N-Lauroylsarcosine (N-Dodecanoyl-N-methylglycine, Sarkosyl L, LS) is an anionic surfactant. Its microbicidal action against herpes simplex type 2 (HSV-2) intravaginal infection in a murine model has been investigated.
Application
N-Lauroylsarcosine may be used as a permeation enhancer in the transdermal drug delivery formulations since it increases the fluidity of stratum corneum lipid structure of the skin†
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
保管分類
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Yeu-Chun Kim et al.
International journal of pharmaceutics, 352(1-2), 129-138 (2007-12-15)
To develop formulations for transdermal drug delivery, this study tested the hypothesis that the anionic surfactant, N-lauroylsarcosine (NLS), and ethanol synergistically increase skin permeability by increasing the fluidity of stratum corneum lipid structure. Skin permeability experiments showed that transdermal delivery
Yoshiaki Furukawa et al.
The Journal of biological chemistry, 285(29), 22221-22231 (2010-04-21)
More than 100 different mutations in Cu,Zn-superoxide dismutase (SOD1) are linked to a familial form of amyotrophic lateral sclerosis (fALS). Pathogenic mutations facilitate fibrillar aggregation of SOD1, upon which significant structural changes of SOD1 have been assumed; in general, however
Kunie Ando et al.
The American journal of pathology, 178(2), 803-816 (2011-02-02)
Many models of human tauopathies have been generated in mice by expression of a human mutant tau with maintained expression of mouse endogenous tau. Because murine tau might interfere with the toxic effects of human mutant tau, we generated a

