A1593
Ampicillin
meets USP testing specifications
別名:
アンピシリン 三水和物, D-(−)-α-アミノベンジルペニシリン
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この商品について
実験式（ヒル表記法）:
C16H19N3O4S · 3H2O
CAS番号:
分子量:
403.45
UNSPSC Code:
51281703
NACRES:
NA.76
PubChem Substance ID:
EC Number:
200-709-7
Beilstein/REAXYS Number:
5399534
MDL number:
Quality Level
agency
USP/NF, meets USP testing specifications
form
solid
color
white
mp
198-200 °C (dec.) (lit.)
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
application(s)
pharmaceutical (small molecule)
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O
InChI
1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1
InChI key
RXDALBZNGVATNY-CWLIKTDRSA-N
General description
化学構造：β-ラクタム
Application
突然変異細胞やトランスフォーム細胞のアンピシリン耐性の選択に使用されます。
Biochem/physiol Actions
ペニシリン骨格の側鎖にアミノ基を持つβ-ラクタム抗生物質です。細菌の細胞膜の内側にあるトランスペプチダーゼを不活性化して細胞壁の合成(ペプチドグリカン架橋結合)を阻害するペニシリンの誘導体です。成長過程の大腸菌に対してのみ殺菌作用があります。耐性機序:β-ラクタマーゼが、アンピシリンのβ-ラクタム環を切断します。抗菌スペクトル:グラム陰性菌、グラム陽性菌。
Packaging
25g
Other Notes
容器は固く閉め、乾燥した、通気の良い場所で保管してください。
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
保管分類
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Nai-Chi Chen et al.
PLoS pathogens, 11(10), e1005203-e1005203 (2015-10-23)
Betanodaviruses cause massive mortality in marine fish species with viral nervous necrosis. The structure of a T = 3 Grouper nervous necrosis virus-like particle (GNNV-LP) is determined by the ab initio method with non-crystallographic symmetry averaging at 3.6 Å resolution.
Kate S Baker et al.
The Lancet. Infectious diseases, 15(8), 913-921 (2015-05-06)
Shigellosis is an acute, severe bacterial colitis that, in high-income countries, is typically associated with travel to high-risk regions (Africa, Asia, and Latin America). Since the 1970s, shigellosis has also been reported as a sexually transmitted infection in men who
Jens T Van Praet et al.
The EMBO journal, 34(4), 466-474 (2015-01-21)
Antinuclear antibodies are a hallmark feature of generalized autoimmune diseases, including systemic lupus erythematosus and systemic sclerosis. However, the processes underlying the loss of tolerance against nuclear self-constituents remain largely unresolved. Using mice deficient in lymphotoxin and Hox11, we report