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Merck

G1522

Gentamicin

solution, suitable for hybridoma, BioReagent

別名:

ガラマイシン, ゲンチオマイシンC

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この商品について

CAS番号:
MDL number:
UNSPSC Code:
12352207
eCl@ss:
42020823
PubChem Substance ID:
NACRES:
NA.76
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製品名

ゲンタマイシン 溶液, Hybri-Max, 50 mg/mL gentamicin, 0.1 μm filtered, BioReagent, suitable for hybridoma

grade

Hybri-Max

Quality Level

sterility

0.1 μm filtered

product line

BioReagent

form

liquid

quality

Prepared in tissue culture grade water.

concentration

50 mg/mL gentamicin

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

color

colorless to light yellow

density

1.000 g/cm3

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, mycoplasma

mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6O[C@@H](CC[C@H]6N)[C@@H](C)N)[C@@H]5O.CN[C@H](C)[C@@H]7CC[C@@H](N)[C@H](O7)O[C@@H]8[C@@H](N)C[C@@H](N)[C@H](O[C@H]9OC[C@](C)(O)[C@H](NC)[C@H]9O)[C@H]8O

InChI

1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1

InChI key

RDEIXVOBVLKYNT-HDZPSJEVSA-N

General description

Chemical structure: aminoglycoside

Application

Gentamicin solution has been used to study its dose-related antipruritic effects on serotonin (5-HT)-induced scratching model. It has also been used in electrophysiological analysis.

Biochem/physiol Actions

作用機序:ゲンタマイシンは、リボソームの30Sサブユニットに結合することで、タンパク質の合成を阻害します。

抗菌スペクトル:テトラサイクリン、クロラムフェニコール、カナマイシン、およびコリスチンに耐性を示す菌株、特に、Pseudomonas、Proteus、StaphylococcusおよびStreptococcusなどのグラム陰性およびグラム陽性菌を含む。

Other Notes

Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Disclaimer

The product is stable at 37° for 5 days and is stored at 2-8°C.


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

保管分類

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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資料

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