PHR1058
クロトリマゾール
Pharmaceutical Secondary Standard; Certified Reference Material
別名:
1-(o-クロロ-α,α-ジフェニルベンジル)イミダゾール, 1-(o-クロロトリチル)イミダゾール, 1-[(2-クロロフェニル)ジフェニルメチル]-1H-イミダゾール
ログインで組織・契約価格をご覧ください。
サイズを選択してください
この商品について
実験式（ヒル表記法）:
C22H17ClN2
CAS番号:
分子量:
344.84
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
245-764-8
MDL number:
format
neat
InChI key
VNFPBHJOKIVQEB-UHFFFAOYSA-N
InChI
1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
SMILES string
Clc1ccccc1C(c2ccccc2)(c3ccccc3)n4ccnc4
grade
certified reference material, pharmaceutical secondary standard
agency
USP 1141002, traceable to Ph. Eur. C2430000
API family
clotrimazole
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
storage temp.
2-30°C
Quality Level
類似した製品をお探しですか？ 訪問 製品比較ガイド
関連するカテゴリー
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Clotrimazole is an imidazole antifungal agent with relatively low toxicity. It is widely used in dermatology and gynaecology applications. Clotrimazole ointments are extensively utilized for the treatment of a wide range of systemic mycoses including candidiasis.
Clotrimazole is an imidazole antifungal agent with relatively low toxicity. It is widely used in dermatology and gynaecology applications. Clotrimazole ointments are extensively utilized for the treatment of a wide range of systemic mycoses including candidiasis.
Application
Clotrimazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7129 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
保管分類
11 - Combustible Solids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
PHR1058-1G-PW: + PHR1058-1G-BULK: + PHR1058-1G:
jan
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Development and validation of HPLC method for determination of clotrimazole and its two degradation products in spray formulation
Hajkova R, et al.
Talanta, 73(3), 483-489 (2007)
Determination of methylparaben, propylparaben, clotrimazole and its degradation products in topical cream by RP-HPLC
Solich P, et al.
Chromatographia, 56(1), S181-S184 (2002)
Chromatographic determination of clotrimazole, ketoconazole and fluconazole in pharmaceutical formulations
Abdel-Moety EM, et al.
Il Farmaco (Societa Chimica Italiana : 1989), 57(11), 931-938 (2002)
Sandra Gemma et al.
Journal of medicinal chemistry, 55(15), 6948-6967 (2012-07-13)
Despite recent progress in the fight against malaria, the emergence and spread of drug-resistant parasites remains a serious obstacle to the treatment of infections. We recently reported the development of a novel antimalarial drug that combines the 4-aminoquinoline pharmacophore of
Barbara A Miller et al.
American journal of physiology. Heart and circulatory physiology, 304(7), H1010-H1022 (2013-02-05)
The second member of the transient receptor potential-melastatin channel family (TRPM2) is expressed in the heart and vasculature. TRPM2 channels were expressed in the sarcolemma and transverse tubules of adult left ventricular (LV) myocytes. Cardiac TRPM2 channels were functional since
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）