PHR1182

パパベリン塩酸塩

Name: パパベリン 塩酸塩
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

6,7-ジメトキシ-1-ベラトリルイソキノリン塩酸塩

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この商品について

実験式（ヒル表記法）:

C₂₀H₂₁NO₄ · HCl

CAS番号:

61-25-6

分子量:

375.85

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823194

EC Number:

200-502-1

Beilstein/REAXYS Number:

3921435

MDL number:

MFCD00012745

主要文書

すべての文書を表示

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InChI

1S/C20H21NO4.ClH/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16;/h5-8,10-12H,9H2,1-4H3;1H

InChI key

UOTMYNBWXDUBNX-UHFFFAOYSA-N

SMILES string

COC1=C(OC)C=C(C(CC2=CC(OC)=C(OC)C=C2)=NC=C3)C3=C1.Cl

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. P0270000, traceable to USP 1496008

API family

papaverine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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General description

Papaverine hydrochloride is the hydrochloride salt of an opiate derivative called papaverine, a benzylisoquinoline compound. It has been found to relax smooth muscles of blood vessels and is used in the management of occlusivity and spasticity of pulmonary, coronary and peripheral arteries.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Papaverine hydrochloride is used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

平滑筋弛緩薬および脳血管拡張薬です。ホスホジエステラ-ゼインヒビタ-です。

Analysis Note

このような2次標準は、USP、EP（PhEur）、BPの1次標準にマルチトレーサビリティを提供します。

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA9001 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

保管分類

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

PHR1182-500MG-PW: + PHR1182-500MG:

jan

試験成績書（COA）

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

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Simultaneous determination of dipyrone and papaverine in pharmaceutical formulation using PLS regression and UV spectrophotometry

do Nascimento AP, et al.

Analytical Letters, 40(5), 975-986 (2007)

The effect of intravenous papaverine hydrochloride on the cerebral circulation

Jayne H W, et al

The Journal of Clinical Investigation, 31(1), 111-114 (1952)

Simultaneous assay of ephedrine hydrochloride, theophylline, papaverine hydrochloride and hydroxyzine hydrochloride in tablets using RP-LC

Boberi B, et al.

Journal of Pharmaceutical and Biomedical Analysis, 21(1), 15-22 (1999)

Spectrophotometric determination of meclozine HCl and papaverine HCl in their pharmaceutical formulations

Abdel-Ghani NT, et al.

Journal of Pharmaceutical and Biomedical Analysis, 28(2), 373-378 (2002)

HPLC and chemometric assisted spectrophotometric methods for simultaneous determination of diprophylline, phenobarbitone and papaverine hydrochloride.

Alaa El-Gindy

Farmaco (Societa chimica italiana : 1989), 60(9), 745-753 (2005-07-19)

Three methods are developed for the simultaneous determination of diprophylline (DP), phenobarbitone (PH) and papaverine hydrochloride (PP). The chromatographic method depends on a high performance liquid chromatographic (HPLC) separation on a reversed-phase C18 column with a mobile phase consisting of

パパベリン 塩酸塩

Pharmaceutical Secondary Standard; Certified Reference Material

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この商品について

主要文書

特性

InChI

InChI key

SMILES string

grade

agency

API family

CofA

technique(s)

application(s)

format

storage temp.

Quality Level

関連するカテゴリー

詳細

General description

Application

Biochem/physiol Actions

Analysis Note

Other Notes

安全性情報

pictograms

signalword

hcodes

pcodes

Hazard Classifications

保管分類

wgk

flash_point_f

flash_point_c

適用法令

PHR1182-500MG-PW: + PHR1182-500MG:

資料

試験成績書（COA）

以前この製品を購入いただいたことがある場合

参考文献

テクニカルサービス

パパベリン塩酸塩