PHR1279
(+)-L-アスコルビン酸ナトリウム
Pharmaceutical Secondary Standard; Certified Reference Material
別名:
L(+)-アスコルビン酸 ナトリウム塩, ビタミンC ナトリウム塩
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この商品について
実験式（ヒル表記法）:
C6H7NaO6
CAS番号:
分子量:
198.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-126-1
Beilstein/REAXYS Number:
3767246
MDL number:
製品名
(+)-L-アスコルビン酸ナトリウム, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
PPASLZSBLFJQEF-RXSVEWSESA-M
InChI
1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1
SMILES string
[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0000039
traceable to USP 1613509
API family
sodium ascorbate
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
220 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.
Application
Sodium ascorbate may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by titrimetry and liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Sodium ascorbate, also known as E301, is a sodium salt of ascorbic acid. It is generally used as an antioxidant in pharmaceutical formulations and food products.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards and pharmacopeia primary standards.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards and pharmacopeia primary standards.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC1682 in the slot below. This is an example certificate only and may not be the lot that you receive.
保管分類
11 - Combustible Solids
wgk
WGK 1
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Sodium Ascorbate
Handbook of Pharmaceutical Excipients 6th edition Pharmaceutical Press, 625-627 (2009)
Sodium Ascorbate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 6997-6998 (2019)
Sodium Ascorbate
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 35(6), 4018-4018 (2018)
Aleksander Hinek et al.
Journal of dermatological science, 75(3), 173-182 (2014-07-13)
Vitamin C (L-ascorbic acid), a known enhancer of collagen deposition, has also been identified as an inhibitor of elastogenesis. Present studies explored whether and how the L-ascorbic acid derivative (+) sodium L-ascorbate (SA) would affect production of collagen and elastic
Qiyi Zhao et al.
Cell, 183(1), 76-93 (2020-09-16)
Mitochondria, which play central roles in immunometabolic diseases, have their own genome. However, the functions of mitochondria-located noncoding RNAs are largely unknown due to the absence of a specific delivery system. By circular RNA (circRNA) expression profile analysis of liver
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