A0580
アラキドニルエタノールアミド
≥97.0% (TLC), oil
別名:
アナンダミド(20:4, n-6), AEA, アナンダミド, アラキドン酸 N-(ヒドロキシメチル)アミド
ログインで組織・契約価格をご覧ください。
サイズを選択してください
この商品について
実験式（ヒル表記法）:
C22H37NO2
CAS番号:
分子量:
347.53
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
製品名
アラキドニルエタノールアミド, ≥97.0% (TLC), oil
InChI
1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-
SMILES string
O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NCCO
InChI key
LGEQQWMQCRIYKG-DOFZRALJSA-N
assay
≥97.0% (TLC)
form
oil
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
color
colorless to light yellow
solubility
ethanol: soluble
density
0.92 g/mL at 25 °C (lit.)
lipid type
omega FAs
shipped in
dry ice
storage temp.
−20°C
Quality Level
Gene Information
rat ... Cnr1(25248)
類似した製品をお探しですか？ 訪問 製品比較ガイド
Application
- 内因性カンナビノイド系と内在性オピオイド系間の相互作用が、帝王切開術を受ける妊婦の術後オピオイド使用に影響を与える可能性：アラキドニルエタノールアミドとオピオイド系との相互作用を調査し、術後疼痛とオピオイド使用の管理改善に役立つ知見を提供しています（Stone et al., 2024）。
Biochem/physiol Actions
CBカンナビノイド受容体およびVR1バニロイド受容体の内因性リガンドであるアラキドン酸誘導体。神経芽細胞腫とニューロンにおいてカルシウム電流を抑制します。MAPキナーゼシグナル伝達経路を活性化します。リンパ球およびヒト乳がん細胞の増殖を抑制し、アポトーシスを誘導します。
Disclaimer
光と湿気を避けて保存してください。
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Cristina Miralpeix et al.
Journal of lipid research, 60(7), 1260-1269 (2019-05-30)
The endocannabinoid (eCB) system regulates energy homeostasis and is linked to obesity development. However, the exact dynamic and regulation of eCBs in the hypothalamus during obesity progression remain incompletely described and understood. Our study examined the time course of responses
Weiwei Dong et al.
PloS one, 9(6), e100436-e100436 (2014-06-21)
Swanson's literature-based discovery focus on resurrecting previously published but neglected knowledge. In this study, we propose a two-step model of the discovery process and generate a hypothesis between anandamide and gastric cancer. Further, the potential relationship was confirmed by follow-up
Devi Rani Sagar et al.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 367(1607), 3300-3311 (2012-10-31)
The analgesic effects of cannabinoid ligands, mediated by CB1 receptors are well established. However, the side-effect profile of CB1 receptor ligands has necessitated the search for alternative cannabinoid-based approaches to analgesia. Herein, we review the current literature describing the impact
Emma Puighermanal et al.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 367(1607), 3254-3263 (2012-10-31)
Exogenous cannabinoids, such as delta9-tetrahydrocannabinol (THC), as well as the modulation of endogenous cannabinoids, affect cognitive function through the activation of cannabinoid receptors. Indeed, these compounds modulate a number of signalling pathways critically implicated in the deleterious effect of cannabinoids
Bala Attili et al.
British journal of pharmacology, 176(10), 1481-1491 (2018-12-28)
Non-invasive in vivo imaging of cannabinoid CB2 receptors using PET is pursued to study neuroinflammation. The purpose of this study is to evaluate the in vivo binding specificity of [18 F]MA3, a CB2 receptor agonist, in a rat model with
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）