CS0720
クエン酸シンターゼアッセイキット
1 kit sufficient for 100 reactions (using a 1 ml cuvette), 1 kit sufficient for 480 reactions (using 96 multiwell plates)
別名:
クエン酸シンターゼ活性テストキット
製品名
クエン酸シンターゼアッセイキット, 1 kit sufficient for 100 reactions (using a 1 ml cuvette), 1 kit sufficient for 480 reactions (using 96 multiwell plates)
usage
kit sufficient for 100 reactions (using a 1 ml cuvette)
kit sufficient for 480 reactions (using 96 multiwell plates)
shipped in
dry ice
storage temp.
−20°C
Quality Level
Gene Information
human ... CS(1431)
Analysis Note
クエン酸合成反応においてDTNBが存在すると産生され、またアセチルCoAの脱アセチル化により生じるTNBを比色測定することで酵素活性を測定します。全反応産物であるTNBの吸収極大は412 nmです。
Biochem/physiol Actions
クエン酸シンタ-ゼはトリカルボン酸 (TCA) サイクルの最初の酵素です。本酵素は炭素2個のアセチルCoAと炭素4個のオキサロ酢酸の反応を触媒して、炭素6個のクエン酸を合成します。本酵素はミトコンドリアマトリックスの唯一のマ-カ-です。
General description
全細胞抽出物や単離ミトコンドリアのクエン酸シンタ-ゼ活性を迅速・簡便に測定するのに必要な全ての試薬が含まれ、ポジティブコントロ-ル酵素も入っています。さらに、ミトコンドリア内膜のインタクト性も試験できます。
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
保管分類
10 - Combustible liquids
Elizabeth A Stoll et al.
The Journal of biological chemistry, 286(44), 38592-38601 (2011-09-09)
Although neurogenesis occurs in discrete areas of the adult mammalian brain, neural progenitor cells (NPCs) produce fewer new neurons with age. To characterize the molecular changes that occur during aging, we performed a proteomic comparison between primary-cultured NPCs from the
Postnatal PPARa Activation and Myostatin Inhibition Exert Distinct yet Complimentary Effects on the Metabolic Profile of Obese Insulin-Resistant Mice
Bernardo,B et al.
PLoS ONE, 5(6) (2010)
Stefan M Gehrig et al.
Experimental physiology, 93(11), 1190-1198 (2008-06-24)
Contraction-mediated injury is a major contributing factor to the pathophysiology of muscular dystrophy and therefore therapies that can attenuate this type of injury have clinical relevance. Systemic administration of insulin-like growth factor-I (IGF-I) has been shown to improve muscle function
Alexander L Pendleton et al.
American journal of physiology. Endocrinology and metabolism, 319(1), E67-E80 (2020-05-13)
Fetal sheep with placental insufficiency-induced intrauterine growth restriction (IUGR) have lower hindlimb oxygen consumption rates (OCRs), indicating depressed mitochondrial oxidative phosphorylation capacity in their skeletal muscle. We hypothesized that OCRs are lower in skeletal muscle mitochondria from IUGR fetuses, due
Sara Anjomani Virmouni et al.
Disease models & mechanisms, 8(3), 225-235 (2015-02-15)
Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused by a GAA repeat expansion mutation within intron 1 of the FXN gene, resulting in reduced levels of frataxin protein. We have previously reported the generation of human FXN yeast
関連コンテンツ
Instructions
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）