D9163
DL-ジチオトレイトール
suitable for electrophoresis, ≥99%
別名:
threo-1,4-ジメルカプト-2,3-ブタンジオール, Cleland試薬, DTT
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この商品について
化学式:
HSCH2CH(OH)CH(OH)CH2SH
CAS番号:
分子量:
154.25
UNSPSC Code:
12161504
NACRES:
NB.22
PubChem Substance ID:
EC Number:
222-468-7
Beilstein/REAXYS Number:
1719757
MDL number:
Quality Level
assay
≥99%
form
powder
reaction suitability
reagent type: reductant
technique(s)
electrophoresis: suitable
mp
40-44 °C, 41-44 °C (lit.)
solubility
H2O: 50 mg/mL, clear, colorless to very faintly yellow
cation traces
heavy metals (as Pb): ≤10 ppm
absorption
≤0.04 at 280 at 0.02 M
storage temp.
2-8°C
SMILES string
O[C@H](CS)[C@H](O)CS
InChI
1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
InChI key
VHJLVAABSRFDPM-QWWZWVQMSA-N
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関連するカテゴリー
Application
SH基を還元状態に保つ試薬です。ジスルフィドを定量的 に還元します。SDS-PAGEのサンプルバッファーに加えることで、タンパク質のジスルフィド結合の還元に効果を発揮します。また、架橋剤であるN,N′-ビス(アクリロイル)シスタミンのジスルフィド結合を還元してポリアクリルアミドゲルのマトリックスを切り離す目的でも用いられます。2-メルカプトエタノールと比較して、刺激性および毒性が抑えられています。通常、2-メルカプトエタノールの使用濃度(5% v/v、700 mM)の7分の1濃度(100 mM)で効果を発揮します。
Analysis Note
還元条件下SDS-PAGE用として試験済み
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
保管分類
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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