M2786
3-マレイミド安息香酸 N-ヒドロキシスクシンイミドエステル
crystalline
別名:
MBS
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この商品について
実験式（ヒル表記法）:
C15H10N2O6
CAS番号:
分子量:
314.25
UNSPSC Code:
12352108
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1505254
Form:
crystalline
製品名
3-マレイミド安息香酸 N-ヒドロキシスクシンイミドエステル, crystalline
InChI key
LLXVXPPXELIDGQ-UHFFFAOYSA-N
SMILES string
O=C1CCC(N1OC(C2=CC=CC(N3C(C=CC3=O)=O)=C2)=O)=O
InChI
1S/C15H10N2O6/c18-11-4-5-12(19)16(11)10-3-1-2-9(8-10)15(22)23-17-13(20)6-7-14(17)21/h1-5,8H,6-7H2
form
crystalline
reaction suitability
reagent type: cross-linking reagent
mp
175-177 °C (lit.)
solubility
DMSO: ≤20 mg/mL
functional group
NHS ester
maleimide
storage temp.
−20°C
Quality Level
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関連するカテゴリー
Application
第一級アミンとスルフヒドリル基に反応性を示す、ヘテロ二官能性架橋剤です。通常は、 まずpH 7.0の緩衝条件下で第一級アミンを含む分子とアミド結合により結合します。その後、同じpHで、スルフヒドリル基を有する化合物にチオエ-テルを介して結合します。酵素免疫複合体やハプテン担体分子複合体の調製に有用です。
3-Maleimidobenzoic acid N-hydroxysuccinimide ester (MBS) has been used as a protein cross-linker. It has been used for the stabilization of actin filaments in plant tissue samples.
3-Maleimidobenzoic acid N-hydroxysuccinimide ester has been used:
- in the fixation of pollen in Arabidopis
- as a component of Murashige and Skoog (MS) medium to stabilize F-actin in Eucalyptus root hairs
- in the fixation of F-actin labelled pollen tubes of Lilium davidii
General description
may require addition of solvent to coupling buffer to at least 5% to maintain solubility
Other Notes
アリルマレイミドのリンカ-は、アルキルマレイミドのリンカ-よりも不安定です。
Biochem/physiol Actions
3-Maleimidobenzoic acid N-hydroxysuccinimide is used as a fixative for the preservation of pollen tube F-actin distribution. It imposes less damage when used on pollen tubes.
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Comparison of F-actin fluorescent labeling methods in pollen tubes of Lilium davidii
Wang L, et al.
Plant Cell Reports, 24(5), 266-270 (2005)
Visualization of Actin Organization and Quantification in Fixed Arabidopsis Pollen Grains and Tubes
Qu X, et al.
Bio-protocol, 10(01), 204-211 (2020)
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